SCHEMBL6076594

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12614443	0.90	RAPGEF4 (0.59)	EPHX1EPHX2MEN1NPC1KMT2A
	SCHEMBL331059	0.84	ALDH1A1 (0.59)	EPHX1EPHX2MEN1NPC1KMT2A
	SCHEMBL331037	0.82	RAPGEF4 (0.48)	EPHX1EPHX2MEN1NPC1KMT2A
	SCHEMBL29113772	0.82	HSD17B10 (0.56)	EPHX1EPHX2MEN1NPC1KMT2A
	SCHEMBL11547302	0.82	CYP3A4 (0.56)	EPHX1EPHX2LMNAHTTRAPGEF4
	SCHEMBL1686571	0.82	LMNA (0.57)	MEN1NPC1KMT2ALMNAADORA3
	SCHEMBL9516529	0.82	LMNA (0.57)	MEN1NPC1KMT2ALMNAADORA3
	SCHEMBL6351833	0.80	FADS1 (0.49)	EPHX1EPHX2MEN1KMT2ALMNA
	SCHEMBL10569557	0.80	LMNA (0.54)	EPHX1EPHX2MEN1NPC1KMT2A
	SCHEMBL13945713	0.77	RAPGEF4 (0.49)	EPHX1EPHX2MEN1NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.