SCHEMBL608532

SCHEMBL608532

Cc1ccc(COO)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGXT P21549 2/20 0.58
PARP10 Q53GL7 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
IDO1 P14902 1/20 0.46
MAOB P27338 2/20 0.46
ACHE P22303 2/20 0.46
KCNH2 Q12809 1/20 0.44
MMP2 P08253 2/20 0.43
MMP12 P39900 2/20 0.43
MMP1 P03956 1/20 0.43
MMP9 P14780 1/20 0.43
CASP3 P42574 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL6346718 0.83 TSHR (0.50) AGXTCA1CA2CA9NPC1
SCHEMBL11786079 0.79 LPL (0.46) CA2IDO1SMN1; SMN2CYP2A6TAAR1
SCHEMBL14201539 0.78 CYP2A6 (0.52) AGXTPARP10IDO1MAOBCYP1A2
SCHEMBL9617939 0.78 AGXT (0.64) AGXTPARP10CA1CA2CA9
SCHEMBL3161372 0.78 AGXT (0.64) AGXTPARP10CA1CA2CA9
SCHEMBL958300 0.78 AGXT (0.64) AGXTPARP10CA1CA2CA9
SCHEMBL13021169 0.78 IDO1 (0.59) CA1CA2CA9NPC1RAB9A
Potassium SCHEMBL586332 0.76 AGXT (0.61) AGXTPARP10CA1CA2CA9
SCHEMBL12378 0.76 AGXT (0.61) AGXTPARP10CA1CA2CA9
Lithium SCHEMBL585057 0.76 AGXT (0.61) AGXTPARP10CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0355997-B1 POLYMERISATION PROCESS AND CATALYST SYSTEM THEREFOR POLYSAR LIMITED (CA) 1993-09-15 EP claimed
US-4943616-A LEWIS ACID AND PEROXIDE, ISOBUTYLENE POLYSAR LIMITED (CA) 1990-07-24 US claimed
US-4908421-A Charging isobutylene, organic peroxy compound, Lewis acid to reaction vessel, polymerizing POLYSAR LIMITED (CA) 1990-03-13 US claimed
EP-0355997-A2 Polymerisation process and catalyst system therefor POLYSAR LIMITED (CA) 1990-02-28 EP claimed
US-4255592-A PEROXIDATION OF METHYL SUBSTITUTED BENZENE IN LIQUID PHASE, ALIPHATIC TERT-HYDROPEROXIDE PROMOTER MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1981-03-10 US claimed
JP-55051031-A None JP disclosed
JP-54157531-A None JP disclosed
US-12551467-B2 Compositions and methods of modulating S-nitrosylation CASE WESTERN RESERVE UNIVERSITY (US) 2026-02-17 US disclosed
US-20240366568-A1 COMPOSITIONS AND METHODS FOR TREATING TISSUE INJURY UNIV CASE WESTERN RESERVE (US) 2024-11-07 US disclosed
CN-118512442-A Compositions and methods for reducing serum cholesterol and PCSK9 卡斯西部储备大学 2024-08-20 CN disclosed
WO-2024155618-A1 COMPOSITIONS AND METHODS FOR TREATING WEIGHT GAIN AND/OR DISORDERS ASSOCIATED WITH ABNORMAL DE NOVO LIPOGENESIS, AND FAT ACCUMULATION CASE WESTERN RESERVE UNIVERSITY (US) 2024-07-25 WO disclosed
CN-111356764-B Compositions and methods for reducing serum cholesterol and PCSK9 卡斯西部储备大学 2024-05-24 CN disclosed
US-5616698-A Polymer-supported solution synthesis of oligosaccharides UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION (CA) 1997-04-01 US disclosed
EP-0355997-B1 POLYMERISATION PROCESS AND CATALYST SYSTEM THEREFOR POLYSAR LIMITED (CA) 1993-09-15 EP disclosed
US-4943616-A LEWIS ACID AND PEROXIDE, ISOBUTYLENE POLYSAR LIMITED (CA) 1990-07-24 US disclosed
US-4908421-A Charging isobutylene, organic peroxy compound, Lewis acid to reaction vessel, polymerizing POLYSAR LIMITED (CA) 1990-03-13 US disclosed
EP-0355997-A2 Polymerisation process and catalyst system therefor POLYSAR LIMITED (CA) 1990-02-28 EP disclosed
US-4255592-A PEROXIDATION OF METHYL SUBSTITUTED BENZENE IN LIQUID PHASE, ALIPHATIC TERT-HYDROPEROXIDE PROMOTER MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1981-03-10 US disclosed
JP-S5551031-A PREPARATION OF PHENOLS MITSUBISHI GAS CHEM CO INC 1980-04-14 JP disclosed
JP-S54157531-A PREPARATION OF PHENOLS MITSUBISHI GAS CHEM CO INC 1979-12-12 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12551467-B2 Compositions and methods of modulating S-nitrosylation AKR1A1, AKR1B1, AKR1D1 AGXT 440/4885PARP10 1884/4885CA1 3586/4885
US-20240366568-A1 COMPOSITIONS AND METHODS FOR TREATING TISSUE INJURY PDK4, AK1, PDK1 AGXT 516/4885PARP10 2529/4885CA1 3036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.