Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086546 | 0.92 | TPH1 (0.34) | GRIN1GRIN2BDAOKMT2ASMN1; SMN2 | |
| SCHEMBL6087279 | 0.87 | ALDH1A1 (0.33) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6086367 | 0.87 | TYMS (0.37) | — | |
| SCHEMBL6086605 | 0.86 | HPGD (0.42) | KMT2AALDH1A1 | |
| SCHEMBL6085665 | 0.86 | TSHR (0.34) | GRIN1GRIN2BDAOKMT2A | |
| SCHEMBL6086149 | 0.85 | MTNR1A (0.35) | GRIN1GRIN2BKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7837061 | 0.84 | TPH1 (0.30) | ALDH1A1 | |
| SCHEMBL6086770 | 0.83 | GRIN1 (0.37) | GRIN1GRIN2BDAOKMT2ASMN1; SMN2 | |
| SCHEMBL6087118 | 0.83 | ROCK2 (0.34) | GRIN1GRIN2B | |
| SCHEMBL7849648 | 0.82 | GRIN1 (0.36) | GRIN1GRIN2BKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |