Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Brilliant Green. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CHKA | P35790 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexamethyl Pararosaniline SCHEMBL455550 | 0.91 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| Hexamethyl Pararosaniline SCHEMBL30271599 | 0.88 | ALDH1A1 (0.65) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| Brilliant Green SCHEMBL2515405 | 0.85 | HPGD (0.50) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| Brilliant Green SCHEMBL1756300 | 0.85 | HPGD (0.50) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| Brilliant Green SCHEMBL2518588 | 0.83 | HPGD (0.44) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| Brilliant Green SCHEMBL2518257 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| Brilliant Green SCHEMBL2519297 | 0.80 | RAB9A (0.54) | ALDH1A1HSD17B10ALOX15MAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL1498089 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TSHRHSD17B10ALOX15TDP1 | |
| Hydrochloric Acid SCHEMBL453811 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| Hydrochloric Acid SCHEMBL30327422 | 0.75 | ALDH1A1 (0.59) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026100708-A1 | PHOTOSENSITIVE RESIN LAMINATE, PHOTOSENSITIVE ELEMENT, AND PATTERN FORMING METHOD | 旭化成株式会社 | 2026-05-15 | — | — | WO | disclosed |
| EP-4713293-A1 | METAL NANOPARTICLES STABILIZED WITH CATIONIC COMPOUNDS CAPABLE OF ABSORBING VISIBLE LIGHT | Fundació Eurecat (ES) | 2026-03-25 | — | — | EP | disclosed |
| US-12332179-B2 | Colliding and reacting molecules and colloids electrophoretically | THOMAS G. MASON (US) | 2025-06-17 | — | — | US | disclosed |
| US-12325646-B2 | Fertigation water treatment | UNIVERSITY OF GUELPH (CA) | 2025-06-10 | — | — | US | disclosed |
| US-20250128238-A1 | SEPARATION MEDIA CONTAINING DYES | DONALDSON COMPANY, INC. | 2025-04-24 | — | — | US | disclosed |
| US-20250024837-A1 | PESTICIDE SYSTEM | BANISH, MICHELE | 2025-01-23 | — | — | US | disclosed |
| WO-2024236162-A1 | METAL NANOPARTICLES STABILIZED WITH CATIONIC COMPOUNDS CAPABLE OF ABSORBING VISIBLE LIGHT | FUNDACIÓ EURECAT (ES) | 2024-11-21 | — | — | WO | disclosed |
| CN-118841644-A | Application of dye molecule as additive in preparation of electrolyte | 中山大学 | 2024-10-25 | — | — | CN | disclosed |
| WO-2024068274-A1 | CATIONICALLY CURABLE ADHESIVE WITH HOLDING-STRENGTH INDICATION | TESA SE (DE) | 2024-04-04 | — | — | WO | disclosed |
| US-20240077980-A1 | TRANSPARENT CONDUCTIVE SUBSTRATE AND A DOUBLE-SIDE PHOTOLITHOGRAPHIC METHOD USING THE SAME | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2024-03-07 | — | — | US | disclosed |
| US-5721287-A | RADIATING IN PRESENCE OF TRANSORBER | KIMBERLY-CLARK WORLDWIDE, INC. | 1998-02-24 | — | — | US | disclosed |
| US-5700850-A | PHOTOSTABILITY; COLORANT AND RADIATION ABSORBER | KIMBERLY-CLARK WORLDWIDE (US) | 1997-12-23 | — | — | US | disclosed |
| US-5683843-A | COLOR TONER WITH ABSORBER AND CARRIER | KIMBERLY-CLARK CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5645964-A | STABILIZERS | KIMBERLY-CLARK CORPORATION (US) | 1997-07-08 | — | — | US | disclosed |
| US-5643356-A | UNSATURATED KETONE SENSITIZER BONDED TO RADIATION TRANSORBER WITH COLOR, MOLECULAR INCLUDENT AND VEHICLES | KIMBERLY-CLARK CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| US-5643701-A | Electrophotgraphic process utilizing mutable colored composition | KIMBERLY-CLARK CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| US-5616443-A | TONER FOR ELECTROGRAPHY | KIMBERLY-CLARK CORPORATION (US) | 1997-04-01 | — | — | US | disclosed |
| EP-0712506-A1 | MUTABLE COMPOSITION AND METHODS OF USE THEREOF | KIMBERLY-CLARK CORPORATION (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004955-A1 | MUTABLE COMPOSITION AND METHODS OF USE THEREOF | KIMBERLY-CLARK CORPORATION (US) | 1995-02-16 | — | — | WO | disclosed |
| US-5240780-A | Pressure sensitive adhesives | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250024837-A1 | PESTICIDE SYSTEM | ACHE, PFAS, FPGS | ALDH1A1 3501/4885TSHR 1848/4885HSD17B10 1533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.