Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089761 | 0.91 | GPR132 (0.49) | SLC26A4KDM4ETDP1PPARGGPR132 | |
| SCHEMBL6089174 | 0.89 | NPC1 (0.43) | KDM4ETDP1PPARGNPC1RAB9A | |
| SCHEMBL6089251 | 0.85 | SLC26A4 (0.49) | SLC26A4PPARGNPC1RAB9ANR4A2 | |
| SCHEMBL6088500 | 0.85 | PTGDR2 (0.46) | KDM4ETDP1PPARGGPR132NPC1 | |
| SCHEMBL6090336 | 0.83 | CYSLTR1 (0.58) | — | |
| SCHEMBL6090860 | 0.83 | PPARG (0.44) | SLC26A4TDP1PPARGNPC1PTGER4 | |
| SCHEMBL6091097 | 0.83 | GPR132 (0.47) | SLC26A4KDM4EGPR132NPC1RAB9A | |
| SCHEMBL6088674 | 0.82 | SLC26A4 (0.63) | SLC26A4TDP1NPC1RAB9ANR4A2 | |
| SCHEMBL6088689 | 0.80 | NPC1 (0.46) | KDM4ETDP1GPR132NPC1RAB9A | |
| SCHEMBL4450809 | 0.80 | NR4A2 (0.58) | SLC26A4KDM4ENR4A2PTGER4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060110430-A1 | Copolymerizable azo compounds and articles containing them | Johnson & Johnson Surgical Vision, Inc. | 2006-05-25 | — | — | US | disclosed |
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |