Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092265 | 0.89 | SERPINE1 (0.46) | PPARGPLA2G2ASERPINE1ABCB1P2RY14 | |
| SCHEMBL5738359 | 0.84 | ADORA3 (0.46) | PPARGPLA2G2ASERPINE1PDE4APDE4B | |
| SCHEMBL6091652 | 0.79 | SERPINE1 (0.54) | PPARGPLA2G2ASERPINE1P2RY14 | |
| SCHEMBL6089976 | 0.77 | PTGES (0.44) | PPARGPLA2G2AABCB1MAPT | |
| SCHEMBL5774922 | 0.76 | MAPK8 (0.43) | PDE4APDE4BPDE4CPDE4DADORA3 | |
| SCHEMBL6091169 | 0.75 | ALDH1A1 (0.46) | PPARGPLA2G2ASERPINE1MAPT | |
| SCHEMBL6091490 | 0.75 | TP53 (0.47) | PLA2G2AABCB1TP53 | |
| SCHEMBL5749488 | 0.74 | PTGER4 (0.46) | PPARGPLA2G2ASERPINE1ABCB1MAPT | |
| SCHEMBL6091628 | 0.73 | PLA2G2A (0.41) | PPARGPLA2G2AABCB1MAPT | |
| SCHEMBL5777724 | 0.73 | SERPINE1 (0.45) | PPARGPLA2G2ASERPINE1MAPTP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | PPARG 481/4885PLA2G2A 982/4885SERPINE1 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.