Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091563 | 0.77 | METAP2 (0.33) | METAP2PPARDPPARA | |
| SCHEMBL29169050 | 0.76 | SLC6A4 (0.38) | ADK | |
| SCHEMBL9189810 | 0.72 | CA2 (0.41) | METAP2PPARA | |
| SCHEMBL25015308 | 0.72 | GABRA1 (0.35) | ADK | |
| SCHEMBL4313725 | 0.72 | ALDH1A1 (0.48) | METAP2 | |
| SCHEMBL17088439 | 0.71 | MAOA (0.44) | ADK | |
| SCHEMBL9856252 | 0.71 | METAP2 (0.35) | METAP2 | |
| SCHEMBL5846711 | 0.71 | SMN1; SMN2 (0.44) | METAP2PPARD | |
| SCHEMBL24919969 | 0.71 | MAOA (0.53) | — | |
| SCHEMBL1306384 | 0.71 | GABRA1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006040644-A2 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED THIOCHROMAN DERIVATIVES | RANBAXY LABORATORIES LIMITED (IN) | 2006-04-20 | — | — | WO | disclosed |