Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.51 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273464 | 1.00 | ACHE (0.51) | ACHENOS3NOS1NOS2HTR2C | |
| SCHEMBL16543142 | 1.00 | ACHE (0.51) | ACHENOS3NOS1NOS2HTR2C | |
| Hydrochloric Acid SCHEMBL30098541 | 0.98 | ACHE (0.50) | ACHENOS3NOS1NOS2HTR2C | |
| SCHEMBL13102425 | 0.89 | ACHE (0.48) | ACHEHTR2CSLC6A4HTR2BAADAT | |
| SCHEMBL14537583 | 0.89 | ACHE (0.48) | ACHEHTR2CSLC6A4HTR2BAADAT | |
| SCHEMBL354107 | 0.89 | ACHE (0.48) | ACHEHTR2CSLC6A4HTR2BAADAT | |
| SCHEMBL1736467 | 0.89 | ACHE (0.48) | ACHEHTR2CSLC6A4HTR2BAADAT | |
| SCHEMBL12352440 | 0.85 | ACHE (0.41) | ACHENOS3NOS1NOS2SLC6A4 | |
| SCHEMBL10069514 | 0.85 | ACHE (0.41) | ACHENOS3NOS1NOS2SLC6A4 | |
| SCHEMBL12352398 | 0.85 | ACHE (0.41) | ACHENOS3NOS1NOS2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199946-B2 | Pyrimidinone carboxamide inhibitors of endothelial lipase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-12-01 | — | — | US | disclosed |
| US-20150065505-A1 | PYRIMIDINONE CARBOXAMIDE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-03-05 | — | — | US | disclosed |
| EP-1592674-B1 | AMINO 1, 3, 5-TRIAZINES N-SUBSTITUTED WITH CHIRAL BICYCLIC RADICALS, PROCESS FOR THEIR PREPARATION, COMPOSITIONS THEREOF AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2014-03-05 | — | — | EP | disclosed |
| US-20120101287-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2012-04-26 | — | — | US | disclosed |
| US-8114991-B2 | Used for the control of a range of harmful weeds | BAYER CROPSCIENCE AG (DE) | 2012-02-14 | — | — | US | disclosed |
| EP-2305655-A2 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators. | Bayer CropScience AG (DE) | 2011-04-06 | — | — | EP | disclosed |
| EP-1592674-A1 | AMINO 1, 3, 5-TRIAZINES N-SUBSTITUTED WITH CHIRAL BICYCLIC RADICALS, PROCESS FOR THEIR PREPARATION, COMPOSITIONS THEREOF AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience GmbH (DE) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004069814-A1 | AMINO 1, 3, 5-TRIAZINES N-SUBSTITUTED WITH CHIRAL BICYCLIC RADICALS, PROCESS FOR THEIR PREPARATION, COMPOSITIONS THEREOF AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2004-08-19 | — | — | WO | disclosed |
| US-20040157739-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157739-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | CYP4Z1, IL4I1, BCAT1 | ACHE 2139/4885NOS3 158/4885NOS1 92/4885 |
| US-20120101287-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | IL4I1, DAO, CYP4Z1 | ACHE 2489/4885NOS3 165/4885NOS1 116/4885 |
| US-20150065505-A1 | PYRIMIDINONE CARBOXAMIDE INHIBITORS OF ENDOTHELIAL LIPASE | LIPG, LPL, PNLIP | ACHE 496/4885NOS3 1239/4885NOS1 1260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.