Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212131 | 0.82 | TLR7 (0.44) | MAPTALDH1A1GAAMAOAADORA3 | |
| SCHEMBL29694218 | 0.82 | TLR7 (0.44) | MAPTALDH1A1GAAMAOAADORA3 | |
| SCHEMBL2369253 | 0.82 | KDM4E (0.36) | ALDH1A1GAAKDM4ESMN1; SMN2GLA | |
| SCHEMBL3817794 | 0.81 | PDE4A (0.37) | ALDH1A1GAAKDM4ESMN1; SMN2GLA | |
| Hydrochloric Acid SCHEMBL5523405 | 0.81 | RAB9A (0.44) | MAPTALDH1A1GAAMAOAADORA3 | |
| SCHEMBL2761000 | 0.81 | ADORA3 (0.41) | ADORA3SMN1; SMN2PDPK1CA12PARP1 | |
| Hydrochloric Acid SCHEMBL10587438 | 0.79 | ALDH1A1 (0.46) | MAPTALDH1A1GAAMAOAADORA3 | |
| SCHEMBL6701751 | 0.79 | ADORA3 (0.52) | MAPTALDH1A1ADORA3KDM4ESMN1; SMN2 | |
| SCHEMBL28312743 | 0.78 | TLR7 (0.44) | ALDH1A1MAOAADORA3OPRM1KCNH2 | |
| SCHEMBL487627 | 0.76 | MAOA (0.42) | ALDH1A1GAAMAOATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912565-B1 | PROCESS FOR PREPARING IMIDAZOQUINOLINAMINES | MINNESOTA MINING & MFG (US) | 2004-04-14 | — | — | EP | claimed |
| US-20040019213-A1 | Process for preparing imidazoquinolinamines | 3M INNOVATIVE PROPERTIES COMPANY | 2004-01-29 | — | — | US | claimed |
| US-6624305-B2 | Reacting a 6H-imidazo(4,5-c) tetrazolo(1,5-a)quinoline with triphenylphosphine and hydrolyzing | 3M INNOVATIVE PROPERTIES COMPANY | 2003-09-23 | — | — | US | claimed |
| US-20030153762-A1 | Process for preparing imidazoquinolinamines | 3M INNOVATIVE PROPERTIES COMPANY | 2003-08-14 | — | — | US | claimed |
| US-20030130516-A1 | PROCESS FOR PREPARING IMIDAZOQUINOLINAMINES | 3M INNOVATIVE PROPERTIES COMPANY | 2003-07-10 | — | — | US | claimed |
| US-20020188127-A1 | Process for preparing imidazoquinolinamines | 3M INNOVATIVE PROPERTIES COMPANY | 2002-12-12 | — | — | US | claimed |
| US-7026482-B2 | Process for preparing imidazoquinolinamines | MEDICIS PHARMACEUTICAL CORPORATION | 2006-04-11 | — | — | US | disclosed |
| US-6897314-B2 | Process for preparing imidazoquinolinamines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-05-24 | — | — | US | disclosed |
| US-20050096470-A1 | Process for preparing imidazoquinolinamines | 3M INNOVATIVE PROPERTIES COMPANY | 2005-05-05 | — | — | US | disclosed |
| EP-0912565-B1 | PROCESS FOR PREPARING IMIDAZOQUINOLINAMINES | MINNESOTA MINING & MFG (US) | 2004-04-14 | — | — | EP | disclosed |
| US-20040019213-A1 | Process for preparing imidazoquinolinamines | 3M INNOVATIVE PROPERTIES COMPANY | 2004-01-29 | — | — | US | disclosed |
| US-6624305-B2 | Reacting a 6H-imidazo(4,5-c) tetrazolo(1,5-a)quinoline with triphenylphosphine and hydrolyzing | 3M INNOVATIVE PROPERTIES COMPANY | 2003-09-23 | — | — | US | disclosed |
| US-6613902-B2 | Induce biosynthesis of cytokines such as interferons, interleukins, and tumor necrosis factor in humans and in mice. | 3M INNOVATIVE PROPERTIES COMPANY | 2003-09-02 | — | — | US | disclosed |
| US-5998619-A | Process for preparing imidazoquinolinamines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0912565-A1 | PROCESS FOR PREPARING IMIDAZOQUINOLINAMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0912564-A1 | PROCESS FOR PREPARING TETRAHYDROIMIDAZOQUINOLINAMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5741908-A | Process for reparing imidazoquinolinamines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1997048704-A1 | PROCESS FOR PREPARING IMIDAZOQUINOLINAMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |
| WO-1997048703-A1 | PROCESS FOR PREPARING TETRAHYDROIMIDAZOQUINOLINAMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |
| US-5693811-A | Process for preparing tetrahdroimidazoquinolinamines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019213-A1 | Process for preparing imidazoquinolinamines | VAT1, QARS1, TALDO1 | MAPT 3519/4885ALDH1A1 1648/4885GAA 1099/4885 |
| US-20050096470-A1 | Process for preparing imidazoquinolinamines | ITPA, INMT, PIP4K2C | MAPT 3755/4885ALDH1A1 1777/4885GAA 260/4885 |
| US-20020188127-A1 | Process for preparing imidazoquinolinamines | VAT1, QARS1, TALDO1 | MAPT 3519/4885ALDH1A1 1648/4885GAA 1099/4885 |
| US-20030130516-A1 | PROCESS FOR PREPARING IMIDAZOQUINOLINAMINES | VAT1, QARS1, TALDO1 | MAPT 3519/4885ALDH1A1 1648/4885GAA 1099/4885 |
| US-20030153762-A1 | Process for preparing imidazoquinolinamines | VAT1, QARS1, TALDO1 | MAPT 3519/4885ALDH1A1 1648/4885GAA 1099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.