SCHEMBL610091

SCHEMBL610091

O=C(c1ccccc1)c1ccc(SN2CCOCC2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.60
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
SMN1; SMN2 Q16637 4/20 0.51
TSHR P16473 4/20 0.51
NPC1 O15118 3/20 0.51
TP53 P04637 2/20 0.51
ALOX15 P16050 2/20 0.51
RAB9A P51151 2/20 0.51
MAPK1 P28482 1/20 0.51
ALDH1A1 P00352 5/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 2/20 0.49
HSD17B10 Q99714 2/20 0.49
LMNA P02545 1/20 0.49
STAT1 P42224 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
NPSR1 Q6W5P4 1/20 0.47
ABCB1 P08183 2/20 0.46
POLB P06746 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9579555 0.81 MAPT (0.49) HPGDMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL609169 0.81 CYP1A1 (0.51) HPGDSMN1; SMN2TSHRNPC1TP53
SCHEMBL15082071 0.79 LMNA (0.52) HPGDMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL11798954 0.79 MGLL (0.48) HPGDMEN1KMT2ASMN1; SMN2TSHR
SCHEMBL12757110 0.79 ALDH1A1 (0.62) HPGDMEN1KMT2ASMN1; SMN2TSHR
SCHEMBL22213019 0.77 KMO (0.57) HPGDMEN1KMT2ASMN1; SMN2TSHR
SCHEMBL20979460 0.77 SMN1; SMN2 (0.43) HPGDSMN1; SMN2TSHRNPC1RAB9A
SCHEMBL20979714 0.77 ALDH1A1 (0.60) HPGDMEN1KMT2ASMN1; SMN2TSHR
SCHEMBL50238 0.77 SMN1; SMN2 (0.74) HPGDMEN1KMT2ASMN1; SMN2TSHR
SCHEMBL11307814 0.76 HSD17B10 (0.57) HPGDMEN1KMT2ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2857446-B1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-03-07 EP disclosed
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
US-20150099823-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-04-09 US disclosed
EP-2857446-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2015-04-08 EP disclosed
US-8334339-B2 Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO., LTD. (JP) 2012-12-18 US disclosed
US-20120041134-A1 CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER COMPOSITION, AND PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed