Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 14/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760481 | 0.86 | ALDH1A1 (0.55) | RAPGEF4ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL6131407 | 0.83 | RAPGEF4 (0.54) | RAPGEF4FFAR4 | |
| SCHEMBL2199650 | 0.81 | RAPGEF4 (0.70) | RAPGEF4FFAR4 | |
| SCHEMBL10695412 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRCYP2C9CYP2C19MEN1 | |
| SCHEMBL28360150 | 0.78 | CYP2C9 (0.49) | RAPGEF4ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL31515077 | 0.78 | RAPGEF4 (0.49) | RAPGEF4NPSR1LMNA | |
| SCHEMBL17858123 | 0.77 | RAPGEF4 (0.71) | RAPGEF4MEN1KMT2A | |
| SCHEMBL4333864 | 0.77 | LMNA (0.60) | ALDH1A1TSHRCYP2C9CYP2C19MEN1 | |
| SCHEMBL13140103 | 0.76 | RAPGEF4 (0.63) | RAPGEF4ALDH1A1NPSR1POLBMEN1 | |
| SCHEMBL24968136 | 0.75 | RAPGEF4 (0.43) | RAPGEF4ALDH1A1TSHRCYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6974878-B2 | Catalyst ligands, catalytic metal complexes and processes using same | SYMYX TECHNOLOGIES, INC. (US) | 2005-12-13 | — | — | US | disclosed |
| US-20040249157-A1 | Catalyst ligands, catalytic metal complexes and processes using same | SYMYX TECHNOLOGIES, INC. | 2004-12-09 | — | — | US | disclosed |
| US-20040242881-A1 | Catalyst ligands, catalytic metal complexes and processes using same | SYMYX TECHNOLOGIES, INC. | 2004-12-02 | — | — | US | disclosed |
| US-20020137934-A1 | Catalyst ligands, catalytic metal complexes and processes using and methods of making same | SYMYX TECHNOLOGIES | 2002-09-26 | — | — | US | disclosed |
| US-6316663-B1 | CATALYTIC ADDITION POLYMERIZATION OF OLEFINS, DIOLEFINS, AND/OR ACETYLENIC COMPOUNDS | SYMYX TECHNOLOGIES, INC. | 2001-11-13 | — | — | US | disclosed |
| EP-1131283-A1 | CATALYST LIGANDS, CATALYTIC METAL COMPLEXES AND PROCESSES USING AND METHODS OF MAKING SAME | SYMYX TECHNOLOGIES (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-2001019786-A1 | CATALYST LIGANDS, CATALYTIC METAL COMPLEXES AND PROCESSES USING AND METHODS OF MAKING SAME | SYMYX TECHNOLOGIES (US) | 2001-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249157-A1 | Catalyst ligands, catalytic metal complexes and processes using same | SOD1, OSTC, ZC3HAV1L | RAPGEF4 2062/4885ALDH1A1 3414/4885TSHR 4215/4885 |
| US-20040242881-A1 | Catalyst ligands, catalytic metal complexes and processes using same | SOD1, OSTC, ZC3HAV1L | RAPGEF4 2062/4885ALDH1A1 3414/4885TSHR 4215/4885 |
| US-20020137934-A1 | Catalyst ligands, catalytic metal complexes and processes using and methods of making same | SOD1, ZC3HAV1L, OSTC | RAPGEF4 2322/4885ALDH1A1 2821/4885TSHR 4109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.