Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131403 | 0.75 | RAPGEF4 (0.54) | RAPGEF4LMNAMEN1KMT2ACYP2C9 | |
| SCHEMBL7573522 | 0.70 | PTGS2 (0.53) | LMNAGAAFTOMEN1KMT2A | |
| SCHEMBL20419768 | 0.68 | FTO (0.65) | RAPGEF4LMNAGAAFTOMEN1 | |
| SCHEMBL14646679 | 0.67 | ALDH1A1 (0.57) | LMNAMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL3001839 | 0.67 | CLCN2 (0.61) | RAPGEF4LMNAGAAFTOMEN1 | |
| SCHEMBL7606289 | 0.66 | LMNA (0.57) | LMNAGAAMEN1KMT2ACYP1A2 | |
| SCHEMBL9987805 | 0.66 | RAPGEF4 (0.50) | RAPGEF4LMNAGAAFTOMEN1 | |
| SCHEMBL20419769 | 0.66 | PTGS2 (0.62) | RAPGEF4LMNAGAAFTOMEN1 | |
| SCHEMBL7760481 | 0.66 | ALDH1A1 (0.55) | RAPGEF4LMNAGAAMEN1KMT2A | |
| SCHEMBL28258477 | 0.65 | KMT2A (0.47) | LMNAMEN1KMT2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3395875-B2 | LASER BEAM-PERMEABLE SUBSTRATE MATERIAL FOR SENSOR APPLICATIONS | COVESTRO DEUTSCHLAND AG (DE) | 2023-01-25 | — | — | EP | disclosed |