Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.37 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27536913 | 0.88 | RXRA (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL394617 | 0.82 | XDH (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10412862 | 0.82 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL541999 | 0.79 | HNF4A (0.43) | FFAR1CYP1A2PTGS1PTGS2KDM4E | |
| SCHEMBL27499513 | 0.78 | FFAR1 (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1978850 | 0.78 | RXRB (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8028952 | 0.78 | GABRG2 (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9349088 | 0.77 | ALDH1A1 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL6732842 | 0.77 | HNF4A (0.42) | FFAR1CYP1A2PTGS1PTGS2KDM4E | |
| SCHEMBL2745941 | 0.77 | CYP1A2 (0.41) | FFAR1CYP1A2PTGS1PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838574-B1 | Dicarba-closo-dodecarborane derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2005-01-04 | — | — | US | disclosed |
| EP-1145718-A1 | DICARBA-closo-DODECABORANE DERIVATIVES | Institute of Medicinal Molecular Design, Inc. (JP) | 2001-10-17 | — | — | EP | disclosed |