Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132759 | 0.86 | DRD2 (0.43) | SMN1; SMN2LMNADRD2DRD4DRD3 | |
| SCHEMBL6132525 | 0.84 | ADRB1 (0.61) | DRD2DRD4DRD3HTTTP53 | |
| Hydrochloric Acid SCHEMBL6132311 | 0.83 | ADRB1 (0.59) | DRD2DRD4DRD3HTTTP53 | |
| SCHEMBL6132931 | 0.80 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2LMNAGAA | |
| Hydrochloric Acid SCHEMBL6132929 | 0.79 | ENPP2 (0.50) | MAPTALDH1A1SMN1; SMN2LMNADRD2 | |
| SCHEMBL13716755 | 0.78 | CCR3 (0.49) | MAPTALDH1A1SMN1; SMN2LMNAALOX12 | |
| SCHEMBL29638934 | 0.77 | OPRM1 (0.47) | ALDH1A1LMNADRD2DRD4DRD3 | |
| SCHEMBL1284884 | 0.77 | OPRM1 (0.44) | MAPTALDH1A1LMNADRD2DRD4 | |
| SCHEMBL28819411 | 0.76 | DRD2 (0.46) | ALDH1A1SMN1; SMN2DRD2DRD4DRD3 | |
| SCHEMBL6132250 | 0.76 | SMN1; SMN2 (0.59) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |