Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132388 | 0.86 | MAPT (0.43) | DRD2DRD4DRD3HTR3EHTR3B | |
| SCHEMBL6132525 | 0.84 | ADRB1 (0.61) | DRD2DRD4DRD3HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL6132311 | 0.83 | ADRB1 (0.59) | DRD2DRD4DRD3HTR3EHTR3B | |
| SCHEMBL6132931 | 0.80 | MAPT (0.49) | ADRB1MEN1KMT2ALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6132929 | 0.79 | ENPP2 (0.50) | DRD2SIGMAR1MEN1KMT2ALMNA | |
| SCHEMBL29638934 | 0.77 | OPRM1 (0.47) | DRD2DRD4DRD3SIGMAR1LMNA | |
| SCHEMBL12665882 | 0.77 | OPRM1 (0.44) | DRD2DRD4DRD3OPRM1OPRD1 | |
| SCHEMBL3576114 | 0.76 | OPRM1 (0.40) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL28819411 | 0.76 | DRD2 (0.46) | DRD2DRD4DRD3SMN1; SMN2OPRM1 | |
| SCHEMBL6133136 | 0.76 | ALDH1A1 (0.52) | DRD2MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |