SCHEMBL6135835

SCHEMBL6135835

COc1ccc(Oc2c(I)cc(C(=O)O)cc2I)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 2/20 0.58
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
NR4A2 P43354 1/20 0.46
PARP10 Q53GL7 1/20 0.46
PCNA P12004 2/20 0.46
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
RXRA P19793 1/20 0.44
TP53 P04637 1/20 0.43
PKM P14618 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4431892 0.87 MAPT (0.48) TPMTCA1CA2PARP10PCNA
SCHEMBL6720943 0.86 TPMT (0.50) TPMTMEN1KMT2APARP10PCNA
SCHEMBL6723673 0.86 TPMT (0.54) TPMTCA1CA2KDM4EMEN1
SCHEMBL237992 0.85 CA1 (0.58) TPMTCA1CA2KDM4EMEN1
SCHEMBL6135971 0.85 PARP10 (0.45) TPMTCA1CA2KDM4EPARP10
SCHEMBL6135849 0.85 PARP10 (0.62) TPMTCA1CA2KMT2APARP10
SCHEMBL4008454 0.85 PCNA (0.61) TPMTCA1CA2PARP10PCNA
SCHEMBL6723577 0.84 CA1 (0.54) TPMTCA1CA2KDM4ERAB9A
SCHEMBL6136046 0.83 PLK1 (0.60) CA1CA2PARP10PCNASMN1; SMN2
SCHEMBL7561681 0.83 KMT2A (0.47) KMT2APARP10PCNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 US disclosed
US-20260041799-A1 HYDROLYSIS-RESISTANT HYDROGELS AND METHODS OF TREATMENT USING SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-02-12 US disclosed
US-20260014282-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES FOR USE IN MEDICAL HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-01-15 US disclosed
US-20250249130-A1 RADIOPAQUE POLYPEPTIDES FOR INJECTABLE COMPOSITIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-08-07 US disclosed
EP-0954299-B1 THYROXINE ANALOGUES HAVING NO SIGNIFICANT HORMONAL ACTIVITY FOR TREATING MALIGNANT TUMOURS OCTAMER INC (US) 2005-07-27 EP disclosed
EP-1024800-B1 THYROXINE ANALOGUES HAVING NO SIGNIFICANT HORMONAL ACTIVITY TO TREAT MALIGNANT TUMORS OCTAMER INC (US) 2002-08-21 EP disclosed
US-6326402-B1 AROMATIC ESTER COMPOUND OCTAMER, INC. 2001-12-04 US disclosed
US-6303621-B1 ADMINISTERING DIIODO THYRONINE ANALOGUE HAVING NO SIGNIFICANT HORMONAL ACTIVITY AND A VINCA ALKALOID SELECTED FROM LEUROSINE, VINCALEUKOBLASTINE, VINBLASTINE, LEUROFORMINE, LEUROSIDINE, LEUROCRISTINE, VINCRISTINE, DEOXY VINBLASTINE OCTAMER, INC. 2001-10-16 US disclosed
EP-0954299-A4 METHOD OF TREATING MALIGNANT TUMORS WITH THYROXINE ANALOGUES HAVING NO SIGNIFICANT HORMONAL ACTIVITY OCTAMER INC (US) 2000-09-06 EP disclosed
US-6017958-A A THERAPEUTIC TREATMENT USING A METHYL ALKYLOXY- OR THIO-PHENYL BENZOATE, AS POTENT, SELECTIVE AND NON-TOXIC ANTI-TUMOR AGENTS FOR TREATING CANCER OCTAMER, INC. (US) 2000-01-25 US disclosed
EP-0954299-A1 METHOD OF TREATING MALIGNANT TUMORS WITH THYROXINE ANALOGUES HAVING NO SIGNIFICANT HORMONAL ACTIVITY Octamer, Inc. (US) 1999-11-10 EP disclosed
US-5922775-A ADMINISTERING A COMPOUND ABLE TO INHIBIT THE INITIAL VELOCITY OF MICROTUBULE PROTEIN ASSEMBLY IN VITRO; SUCH AS 1-(3,5-DIIODO-4-(4'-METHOXYPHENOXY)-PHENYL)-ETHANONE (DIPE) OCTAMER, INC. (US) 1999-07-13 US disclosed
US-5736576-A ADMINISTERING METHYL 3,5-DIIODO-4-(4*-METHOXYPHENOXY)BENZOATE OCTAMER, INC. (US) 1998-04-07 US disclosed
WO-1997046228-A1 METHOD OF TREATING MALIGNANT TUMORS WITH THYROXINE ANALOGUES HAVING NO SIGNIFICANT HORMONAL ACTIVITY OCTAMER, INC. (US) 1997-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS KLK3, BRDT, BPHL TPMT 4080/4885CA1 390/4885CA2 2180/4885
US-20260014282-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES FOR USE IN MEDICAL HYDROGELS IAPP, NPPA, ARG1 TPMT 4779/4885CA1 226/4885CA2 609/4885
US-20260041799-A1 HYDROLYSIS-RESISTANT HYDROGELS AND METHODS OF TREATMENT USING SAME PAM, CRYAA, COL1A1 TPMT 3261/4885CA1 844/4885CA2 1401/4885
US-20250249130-A1 RADIOPAQUE POLYPEPTIDES FOR INJECTABLE COMPOSITIONS IAPP, IGFBP6, NPPA TPMT 4869/4885CA1 1262/4885CA2 3237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.