Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2542389 | 0.97 | DNM1 (0.40) | DNM1CES2CES1LMNAALDH1A1 | |
| SCHEMBL20853667 | 0.90 | CES2 (0.41) | CES2CES1 | |
| SCHEMBL15065991 | 0.86 | CES2 (0.39) | CES2CES1 | |
| SCHEMBL10711653 | 0.86 | CES2 (0.39) | CES2CES1 | |
| SCHEMBL7900186 | 0.85 | CES2 (0.38) | DNM1CES2CES1 | |
| SCHEMBL1033647 | 0.82 | BBOX1 (0.30) | — | |
| SCHEMBL16146094 | 0.81 | DNM1 (0.40) | DNM1CES2LMNAALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL17004781 | 0.81 | GPR84 (0.37) | CES2CA2PSMD14PLA2G1BMMP2 | |
| SCHEMBL7718266 | 0.81 | DNM1 (0.40) | DNM1CES2LMNAALDH1A1HSD17B10 | |
| SCHEMBL15689292 | 0.79 | DNM1 (0.47) | DNM1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100418420-C | Fungicide, composition thereof, use and fungicidal method thereof | AJINOMOTO KK (JP) | 2008-09-17 | — | — | CN | disclosed |
| EP-1285579-B1 | Bactericidal guanidine derivatives, dermally applicable composition, washing composition, and antibacterial fibre aggregate | AJINOMOTO KK (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-20030162838-A1 | Bactericide, antiseptic, dermally applicable composition, washing composition, antibacterial fiber aggregate, method for eradicating a microorganism, and method for inhibiting the proliferation of a microorgamism | AJINOMOTO CO., INC. (JP) | 2003-08-28 | — | — | US | disclosed |
| CN-1401240-A | Fungicide, composition thereof, use and fungicidal method thereof | AJINOMOTO KK (JP) | 2003-03-12 | — | — | CN | disclosed |
| EP-1285579-A1 | Bactericidal guanidine derivatives, dermally applicable composition, washing composition, and antibacterial fibre aggregate | Ajinomoto Co., Inc. (JP) | 2003-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162838-A1 | Bactericide, antiseptic, dermally applicable composition, washing composition, antibacterial fiber aggregate, method for eradicating a microorganism, and method for inhibiting the proliferation of a microorgamism | ARG1, ALKBH1, GANC | DNM1 1980/4885CES2 1147/4885CA2 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.