Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207936 | 1.00 | ADRA1A (0.32) | ADRA1ATSHRCYP2A6 | |
| SCHEMBL9225445 | 0.79 | GPR84 (0.33) | — | |
| SCHEMBL4053225 | 0.78 | — | — | |
| SCHEMBL7086196 | 0.75 | GPR84 (0.45) | TSHR | |
| SCHEMBL8194399 | 0.71 | HCAR2 (0.32) | — | |
| SCHEMBL7482610 | 0.71 | CA2 (0.32) | — | |
| SCHEMBL4267778 | 0.71 | — | — | |
| SCHEMBL15794861 | 0.69 | DAO (0.39) | ADRA1ATSHR | |
| SCHEMBL14560346 | 0.68 | SRC (0.43) | TSHR | |
| SCHEMBL4171179 | 0.68 | GABRA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476423-A4 | ARYLSULFONAMIDOBENZYLIC COMPOUNDS | TULARIK INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1476423-A2 | ARYLSULFONAMIDOBENZYLIC COMPOUNDS | Tularik Inc. (US) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003063576-A2 | ARYLSULFONAMIDOBENZYLIC COMPOUNDS | TULARIK INC. (US) | 2003-08-07 | — | — | WO | disclosed |