Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16608098 | 0.87 | ALDH1A1 (0.38) | CYP19A1NQO2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL2025462 | 0.78 | CASP1 (0.41) | CYP19A1NQO2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL2529901 | 0.78 | ACHE (0.46) | CYP19A1NQO2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL21264353 | 0.78 | MAPT (0.47) | FYNCYP19A1NQO2CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL5484796 | 0.76 | CASP1 (0.39) | CYP19A1NQO2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL17000445 | 0.76 | CYP3A4 (0.44) | ALDH1A1CYP3A4TSHRTUBB4ATUBB | |
| Hydrochloric Acid SCHEMBL8521226 | 0.76 | MAPT (0.46) | CYP19A1NQO2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL11512951 | 0.73 | GAA (0.43) | CYP19A1NQO2POLBGAA | |
| SCHEMBL29974990 | 0.73 | IMPDH2 (0.38) | CYP19A1NQO2TSHRMAPK1TUBB4A | |
| SCHEMBL214933 | 0.73 | IMPDH2 (0.38) | CYP19A1NQO2TSHRMAPK1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1231889-B1 | DIRECT HAIR DYES AND USE THEREOF | HENKEL KGAA (DE) | 2005-12-14 | — | — | EP | disclosed |
| EP-1218344-B1 | OXIDATION COLORANT STARTING PRODUCTS | HENKEL KGAA (DE) | 2005-08-17 | — | — | EP | disclosed |
| EP-1212032-B1 | NEW DIRECT HAIR COLORANTS | HENKEL KGAA (DE) | 2005-05-04 | — | — | EP | disclosed |
| US-20050086746-A1 | Direct hair dyes and use thereof | MUSANG DEVELOPMENT CORP. | 2005-04-28 | — | — | US | disclosed |
| EP-1185234-B1 | NEW COUPLING COMPONENTS FOR OXIDATION HAIR COLORANTS | HENKEL KGAA (DE) | 2005-02-09 | — | — | EP | disclosed |
| US-6835211-B1 | Comprises 1,4-dihydroxy-6-chloro-7-(3'-methylphenoxy)-anthraquinone; improved colorfastness | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-12-28 | — | — | US | disclosed |
| EP-1212031-B1 | USE OF 2-NITRO-P-PHENYLENE DIAMINE DERIVATIVES AS DIRECT COLORANTS | HENKEL KGAA (DE) | 2004-08-04 | — | — | EP | disclosed |
| EP-1231889-A2 | DIRECT HAIR DYES AND USE THEREOF | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-08-21 | — | — | EP | disclosed |
| EP-1218344-A2 | OXIDATION COLORANT STARTING PRODUCTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-07-03 | — | — | EP | disclosed |
| EP-1212031-A1 | USE OF 2-NITRO-P-PHENYLENE DIAMINE DERIVATIVES AS DIRECT COLORANTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-06-12 | — | — | EP | disclosed |
| EP-1185234-A1 | NEW COUPLING COMPONENTS FOR OXIDATION HAIR COLORANTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-03-13 | — | — | EP | disclosed |
| WO-2001026615-A2 | DIRECT HAIR DYES CONTAINING A HYDROXYANTHROQUINONE DERIVATIVE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-04-19 | — | — | WO | disclosed |
| WO-2001021143-A1 | USE OF 2-NITRO-P-PHENYLENE DIAMINE DERIVATIVES AS DIRECT COLORANTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-03-29 | — | — | WO | disclosed |
| WO-2001000152-A1 | NEW COUPLING COMPONENTS FOR OXIDATION HAIR COLORANTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-01-04 | — | — | WO | disclosed |
| WO-2000076977-A2 | OXIDATION COLORANT STARTING PRODUCTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050086746-A1 | Direct hair dyes and use thereof | CYP7B1, CYP26A1, NDUFA6 | FYN 3405/4885CYP19A1 183/4885NQO2 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.