Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29974990 | 1.00 | IMPDH2 (0.38) | IMPDH2PTGS2TAAR1DHFRGAA | |
| SCHEMBL11511084 | 0.84 | DHFR (0.40) | IMPDH2DHFRGAAMAPTKDM4E | |
| SCHEMBL2530490 | 0.82 | MAPT (0.37) | IMPDH2GAAMAPTKDM4ETSHR | |
| SCHEMBL13359272 | 0.82 | PTGS2 (0.50) | PTGS2TAAR1GAAMAPTKDM4E | |
| SCHEMBL18304159 | 0.80 | PTGS2 (0.39) | PTGS2TAAR1DHFRCYP19A1PDE5A | |
| SCHEMBL16608098 | 0.79 | ALDH1A1 (0.38) | GAAMAPTTSHRMAPK1CYP19A1 | |
| SCHEMBL14612535 | 0.77 | POLB (0.35) | PTGS2TAAR1DHFRGAAMAPT | |
| SCHEMBL11511918 | 0.77 | CYP1A2 (0.41) | GAAMAPTKDM4ETSHRHTT | |
| SCHEMBL2154314 | 0.74 | GPR84 (0.39) | TAAR1GAAMAPTKDM4ETSHR | |
| SCHEMBL10871753 | 0.74 | TSHR (0.46) | GAAMAPTKDM4ETSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8043385-B2 | Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof | L'OREAL S.A. (FR) | 2011-10-25 | — | — | US | claimed |
| US-8002847-B2 | Composition for oxidation dyeing keratin fibres comprising a cationic cellulose ether, a weakly oxyethylenated sorbitan fatty acid ester and oxidation dyes | L 'OREAL S.A. (FR) | 2011-08-23 | — | — | US | claimed |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | L'OREAL S.A. (FR) | 2010-11-04 | — | — | US | claimed |
| US-20100263138-A1 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'OREAL S.A. (FR) | 2010-10-21 | — | — | US | claimed |
| EP-0852135-B2 | Oxidative dyeing composition for keratin fibres and dyeing method employing it | OREAL (FR) | 2008-03-19 | — | — | EP | claimed |
| US-7141079-B2 | Oxidation dyeing composition for keratinous fibers and dyeing method using same | L′Oreal (FR) | 2006-11-28 | — | — | US | claimed |
| US-20060021156-A1 | Composition for the oxidation dyeing of keratinous fibres containing a laccase and dyeing method using this composition | L'OREAL S.A. | 2006-02-02 | — | — | US | claimed |
| US-6890362-B2 | Oxidation dyeing composition for keratinous fibers and dyeing method using same | L'OREAL, S.A. (FR) | 2005-05-10 | — | — | US | claimed |
| EP-1002518-B1 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | OREAL (FR) | 2004-12-08 | — | — | EP | claimed |
| EP-0966250-B1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES COMPRISING 2-CHLORO 6 METHYL 3-AMINOPHENOL, AN OXIDATION BASE AND AN ADDITIONAL COUPLER, AND DYEING METHOD | OREAL (FR) | 2004-11-17 | — | — | EP | claimed |
| WO-1999017733-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES AND DYEING METHOD USING SAID COMPOSITION | L'OREAL (FR) | 1999-04-15 | — | — | WO | claimed |
| WO-1999011228-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES COMPRISING 2-CHLORO 6 METHYL 3-AMINOPHENOL, AN OXIDATION BASE AND AN ADDITIONAL COUPLER, AND DYEING METHOD | L'OREAL (FR) | 1999-03-11 | — | — | WO | claimed |
| EP-0852135-A1 | Oxidative dyeing composition for keratin fibres and dyeing method employing it | L'OREAL (FR) | 1998-07-08 | — | — | EP | claimed |
| US-5752983-A | Composition for oxidation dyeing of keratinous fibres comprising an oxidation base, a coupler, and 4-hydroxyindole as coupler and dyeing process with this composition | L'OREAL (FR) | 1998-05-19 | — | — | US | claimed |
| EP-0819425-A1 | Oxidative hair dye composition and the dyeing process using such a composition | L'OREAL (FR) | 1998-01-21 | — | — | EP | claimed |
| US-5690696-A | HAIR DYES | L'OREAL (FR) | 1997-11-25 | — | — | US | claimed |
| EP-0722713-B1 | Composition for oxidative dyeing of keratin fibers and process of dyeing using that composition | OREAL (FR) | 1997-08-06 | — | — | EP | claimed |
| EP-0722713-A1 | Composition for oxidative dyeing of keratin fibers and process of dyeing using that composition | L'OREAL (FR) | 1996-07-24 | — | — | EP | claimed |
| EP-0722710-A1 | Keratinous fiber oxidation dyeing composition and the dyeing process using this composition | L'OREAL (FR) | 1996-07-24 | — | — | EP | claimed |
| US-4904275-A | OXIDIZER | L'OREAL (FR) | 1990-02-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060021156-A1 | Composition for the oxidation dyeing of keratinous fibres containing a laccase and dyeing method using this composition | TYR, KRT18, LPO | IMPDH2 642/4885PTGS2 2082/4885TAAR1 1469/4885 |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | KRT18, KRTCAP2, FASN | IMPDH2 3419/4885PTGS2 2782/4885TAAR1 3084/4885 |
| US-20100263138-A1 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | KRT18, TUBB3, VIM | IMPDH2 3881/4885PTGS2 4434/4885TAAR1 2919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.