Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.50 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154032 | 0.90 | SLC6A12 (0.56) | MEN1KMT2AKDM4EMCHR1SMN1; SMN2 | |
| SCHEMBL5118863 | 0.89 | KDM4E (0.54) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6154012 | 0.88 | OPRK1 (0.55) | MEN1KMT2AKDM4EMCHR1SMN1; SMN2 | |
| SCHEMBL3491711 | 0.86 | MEN1 (0.55) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8070227 | 0.83 | ALDH1A1 (0.68) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3493730 | 0.83 | MAPK1 (0.67) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4225304 | 0.82 | MCHR1 (0.54) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6153323 | 0.81 | SIGMAR1 (0.60) | ALDH1A1KDM4EHSD17B10MCHR1SIGMAR1 | |
| SCHEMBL28164487 | 0.81 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EHSD17B10SMN1; SMN2GAA | |
| SCHEMBL6153565 | 0.80 | SIGMAR1 (0.59) | ALDH1A1KDM4EHSD17B10MCHR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | MEN1 1993/4885KMT2A 1307/4885ALDH1A1 2454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.