Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158814 | 0.93 | PRKDC (0.37) | KDM4EALDH1A1PDE3BPDE3AERAP1 | |
| SCHEMBL6156220 | 0.89 | PDE3B (0.46) | PDE3BPDE3APRKDC | |
| SCHEMBL8371288 | 0.88 | PDE3B (0.39) | ALDH1A1PDE3BPDE3APRKDC | |
| SCHEMBL6165736 | 0.86 | PTPN1 (0.38) | KDM4EALDH1A1HPGDPDE3BPDE3A | |
| SCHEMBL6156255 | 0.85 | MEN1 (0.38) | KDM4EALDH1A1HPGDPDE3BPDE3A | |
| SCHEMBL6156060 | 0.84 | PDE3B (0.37) | ALDH1A1PDE3BPDE3APRKDC | |
| SCHEMBL6155515 | 0.82 | RAB9A (0.33) | KDM4EALDH1A1HPGDPDE3BPDE3A | |
| SCHEMBL6156254 | 0.80 | KDM4E (0.35) | KDM4EALDH1A1GLAP4HBHPGD | |
| SCHEMBL6155845 | 0.80 | KMT2A (0.34) | KDM4EALDH1A1GLAHPGDRAB9A | |
| SCHEMBL7784158 | 0.76 | ALDH1A1 (0.45) | KDM4EALDH1A1GAAHPGDP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894805-B1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2005-02-09 | — | — | EP | disclosed |
| EP-0894805-A1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 1999-02-03 | — | — | EP | disclosed |