Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 8/20 | 0.43 |
| ▸ | CASP3 | P42574 | 9/20 | 0.39 |
| ▸ | CASP7 | P55210 | 6/20 | 0.39 |
| ▸ | CASP6 | P55212 | 5/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157558 | 0.94 | KMT2A (0.48) | CASP1KMT2AHPGDALDH1A1TSHR | |
| SCHEMBL6157985 | 0.88 | CASP3 (0.41) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL6160437 | 0.87 | CASP1 (0.52) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL6159833 | 0.84 | CASP1 (0.54) | CASP1KMT2AALDH1A1MEN1TSHR | |
| SCHEMBL6161919 | 0.83 | CASP1 (0.47) | CASP1KMT2AHPGDMEN1 | |
| SCHEMBL6161964 | 0.81 | CASP1 (0.54) | CASP1KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL6157421 | 0.80 | CASP1 (0.41) | CASP1CASP3CASP7CASP8KMT2A | |
| SCHEMBL6158900 | 0.80 | CASP1 (0.38) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL6158761 | 0.80 | CASP1 (0.38) | CASP1CASP3CASP7CASP6CASP8 | |
| SCHEMBL7487986 | 0.80 | CASP1 (0.55) | CASP1CASP3CASP7CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | claimed |
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | disclosed |