Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 17/20 | 0.41 |
| ▸ | CASP1 | P29466 | 17/20 | 0.41 |
| ▸ | CASP7 | P55210 | 14/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 13/20 | 0.39 |
| ▸ | CASP6 | P55212 | 12/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157827 | 0.88 | CASP1 (0.43) | CASP3CASP1CASP7CASP8CASP6 | |
| SCHEMBL6160437 | 0.86 | CASP1 (0.52) | CASP3CASP1CASP7CASP8CASP6 | |
| SCHEMBL6157558 | 0.86 | KMT2A (0.48) | CASP1 | |
| SCHEMBL6161964 | 0.81 | CASP1 (0.54) | CASP1 | |
| SCHEMBL6161919 | 0.79 | CASP1 (0.47) | CASP1 | |
| SCHEMBL6158761 | 0.79 | CASP1 (0.38) | CASP3CASP1CASP7CASP8CASP6 | |
| SCHEMBL6158900 | 0.76 | CASP1 (0.38) | CASP3CASP1CASP7CASP8CASP6 | |
| SCHEMBL6157870 | 0.76 | CASP1 (0.56) | CASP1 | |
| SCHEMBL6158570 | 0.76 | CASP1 (0.49) | CASP1 | |
| SCHEMBL6157542 | 0.74 | MTNR1A (0.49) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | claimed |
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | disclosed |