Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158933 | 0.90 | KCNA5 (0.38) | KCNA5MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6264342 | 0.75 | HPGD (0.49) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL6156971 | 0.72 | MAPK8 (0.43) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL6158896 | 0.71 | GPR88 (0.39) | ALDH1A1 | |
| SCHEMBL6157584 | 0.70 | KCNA5 (0.43) | KCNA5MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6267497 | 0.69 | HPGD (0.51) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL6266482 | 0.69 | KMT2A (0.43) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL6158915 | 0.68 | GPR88 (0.35) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL6156056 | 0.68 | SLC6A5 (0.47) | NPC1RAB9ASLC6A5 | |
| SCHEMBL6156568 | 0.67 | CA1 (0.64) | MEN1KMT2AALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501813-A2 | BENZOTHIADIAZEPINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Astrazeneca AB (SE) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003091232-A2 | BENZOTHIADIAZEPINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2003-11-06 | — | — | WO | disclosed |