Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160652 | 0.83 | ENPP2 (0.41) | ENPP2SIRT2PSMB5PPARAPPARD | |
| SCHEMBL3996205 | 0.79 | PSMB5 (0.43) | ENPP2SIRT2PSMB5PPARAPPARD | |
| SCHEMBL6160660 | 0.78 | ENPP2 (0.42) | ENPP2SIRT2PSMB5PPARAPPARD | |
| SCHEMBL6160047 | 0.77 | SIRT2 (0.39) | SIRT2PSMB5LMNAPPARAPPARD | |
| SCHEMBL4962776 | 0.74 | TRPM8 (0.54) | PSMB5LMNAMAPK1PPARAPPARD | |
| SCHEMBL3996571 | 0.73 | PSMB5 (0.43) | SIRT2PSMB5PPARAPPARD | |
| SCHEMBL6160055 | 0.72 | SIRT2 (0.41) | ENPP2SIRT2PSMB5LMNAPPARA | |
| SCHEMBL6161238 | 0.72 | SLC2A1 (0.44) | SIRT2PPARAPPARD | |
| SCHEMBL6160658 | 0.71 | SIRT2 (0.43) | ENPP2SIRT2PPARAPPARD | |
| SCHEMBL2448991 | 0.68 | ALDH1A1 (0.59) | HCAR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517680-A1 | BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA | Astrazeneca AB (SE) | 2005-03-30 | — | — | EP | claimed |
| WO-2004000295-A1 | BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA | ASTRAZENECA AB (SE) | 2003-12-31 | — | — | WO | claimed |