Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160658 | 0.91 | SIRT2 (0.43) | ENPP2PPARAPPARDALDH1A1SIRT2 | |
| SCHEMBL6160055 | 0.91 | SIRT2 (0.41) | ENPP2PPARAPPARDALDH1A1SIRT2 | |
| SCHEMBL3996205 | 0.80 | PSMB5 (0.43) | ENPP2PPARAPPARDALDH1A1SIRT2 | |
| SCHEMBL6160652 | 0.78 | ENPP2 (0.41) | ENPP2PPARAPPARDALDH1A1SIRT2 | |
| SCHEMBL6161235 | 0.78 | ABCC8 (0.43) | ENPP2PPARAPPARDSIRT2PSMB5 | |
| SCHEMBL4962776 | 0.76 | TRPM8 (0.54) | PPARAPPARDALDH1A1PPARGPTGES | |
| SCHEMBL6161238 | 0.72 | SLC2A1 (0.44) | PPARAPPARDALDH1A1SIRT2PPARG | |
| SCHEMBL3996571 | 0.71 | PSMB5 (0.43) | PPARAPPARDSIRT2PSMB5ABCB1 | |
| SCHEMBL6160047 | 0.70 | SIRT2 (0.39) | PPARAPPARDALDH1A1SIRT2PPARG | |
| SCHEMBL2448991 | 0.70 | ALDH1A1 (0.59) | ALDH1A1ABCB1FFAR1KMT2APTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517680-A1 | BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA | Astrazeneca AB (SE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000295-A1 | BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA | ASTRAZENECA AB (SE) | 2003-12-31 | — | — | WO | disclosed |