Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134734 | 0.84 | LMNA (0.61) | ARNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7791354 | 0.79 | PLAU (0.72) | ARHIF1APLAUHPGDSMN1; SMN2 | |
| SCHEMBL1883726 | 0.77 | MEN1 (0.64) | ARHIF1APLAUHPGDSMN1; SMN2 | |
| SCHEMBL7319886 | 0.75 | LMNA (0.69) | ARHIF1APLAUPOLBSMN1; SMN2 | |
| SCHEMBL7320847 | 0.74 | PKM (0.64) | ARHIF1APLAUNPC1SMN1; SMN2 | |
| SCHEMBL2824645 | 0.72 | AR (0.67) | ARHIF1APLAUNPC1POLB | |
| SCHEMBL7789908 | 0.72 | HIF1A (0.62) | ARHIF1APLAUNPC1HPGD | |
| SCHEMBL29134733 | 0.72 | NR3C1 (0.45) | ARNPC1POLBHPGDSMN1; SMN2 | |
| SCHEMBL29134735 | 0.70 | FABP4 (0.43) | NPC1POLBHPGDSMN1; SMN2MEN1 | |
| SCHEMBL422787 | 0.69 | RAB9A (0.62) | NPC1POLBHPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117298108-A | Androgen receptor and glucocorticoid receptor dual-target inhibitor and application thereof | 浙江师范大学 | 2023-12-29 | — | — | CN | disclosed |