Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166017 | 0.82 | HTT (0.39) | — | |
| SCHEMBL6164973 | 0.80 | DHODH (0.36) | DHODH | |
| SCHEMBL6166081 | 0.80 | BRD4 (0.34) | OPRM1 | |
| SCHEMBL6166482 | 0.79 | DHODH (0.36) | DHODH | |
| SCHEMBL6168419 | 0.79 | DHODH (0.42) | DHODHOPRM1 | |
| SCHEMBL6776388 | 0.77 | OPRM1 (0.38) | DHODHOPRM1 | |
| SCHEMBL6769850 | 0.77 | OPRM1 (0.38) | DHODHOPRM1 | |
| SCHEMBL6164331 | 0.75 | DHODH (0.34) | DHODH | |
| SCHEMBL6168332 | 0.74 | ALDH1A1 (0.47) | DHODHOPRM1 | |
| SCHEMBL6770751 | 0.74 | OPRM1 (0.45) | DHODHOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177185-B1 | 4, 5, 6, 7-TETRAHYDROINDAZOLE DERIVATIVES AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2005-04-20 | — | — | EP | disclosed |
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |