Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Tetrylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.89 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.89 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.89 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.80 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.80 |
| ▸ | ATM | Q13315 | 1/20 | 0.80 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrylammonium SCHEMBL3722218 | 1.00 | TSHR (0.89) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL5142182 | 1.00 | TSHR (0.89) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL1035999 | 1.00 | TSHR (0.89) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL1419554 | 0.95 | TSHR (0.80) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL9130306 | 0.95 | TSHR (0.80) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL28731470 | 0.95 | TSHR (0.80) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL8341373 | 0.95 | TSHR (0.80) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL7160072 | 0.95 | TSHR (0.80) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL283360 | 0.95 | TSHR (0.80) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Tetrylammonium SCHEMBL228998 | 0.95 | KDM4E (0.90) | TSHRNFKB1KCNA1KDM4EPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350143-B1 | PROCESS FOR DEACTIVATION OF AN OLEFIN OLIGOMERIZATION CATALYST | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2024-05-15 | — | — | EP | claimed |
| CN-107082877-A | A kind of method for preparing nontransparent type polysiloxane polycarbonate random copolymer | 中山市通彩化工科技有限公司 | 2017-08-22 | — | — | CN | claimed |
| EP-2239056-B1 | Catalyst composition and process for oligomerization of ethylene | SAUDI BASIC IND CORP (SA) | 2011-07-20 | — | — | EP | claimed |
| EP-0591810-B1 | Electrolyte for use in an electrolytic capacitor and the electrolytic capacitor | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1997-12-29 | — | — | EP | claimed |
| US-20250034146-A1 | ELECTRO-PHOTOCHEMICAL SYNTHESIS OF 1,2,4-TRIAZOLO-[4,3-A]PYRAZINE | PURDUE RESEARCH FOUNDATION (US) | 2025-01-30 | — | — | US | disclosed |
| WO-2023190512-A1 | POLYESTER RESIN PELLET AND METHOD FOR PRODUCING POLYESTER RESIN | 三菱ケミカル株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2022045219-A1 | METHOD FOR PRODUCING COMPOSITION FOR NON-PHOTOSENSITIVE UPPER FILM FORMATION, PATTERN FORMATION METHOD, AND METHOD FOR PRODUCING ELECTRONIC DEVICE | 富士フイルム株式会社 | 2022-03-03 | — | — | WO | disclosed |
| WO-2022004811-A1 | POLYETHYLENE FURANOATE, HIGHLY-VISCOUS POLYETHYLENE FURANOATE MANUFACTURING METHOD, POLYESTER COMPOSITION, POLYESTER BOTTLE, POLYESTER BOTTLE MANUFACTURING METHOD, AND BEVERAGE PRODUCT | キリンホールディングス株式会社 | 2022-01-06 | — | — | WO | disclosed |
| CN-111732898-B | CMP slurry composition and method of polishing patterned tungsten wafer using the same | 三星SDI株式会社 | 2021-12-07 | — | — | CN | disclosed |
| WO-2021131746-A1 | POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, AND RESIST FILM | DIC株式会社 | 2021-07-01 | — | — | WO | disclosed |
| WO-2021106537-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION, PATTERN FORMING METHOD, AND ELECTRONIC DEVICE MANUFACTURING METHOD | 富士フイルム株式会社 | 2021-06-03 | — | — | WO | disclosed |
| CN-111732898-A | CMP slurry composition and method of polishing patterned tungsten wafer using the same | 三星SDI株式会社 | 2020-10-02 | — | — | CN | disclosed |
| CN-1054850-C | Piperazine compounds used in therapy | WELLCOME FOUND (GB) | 2000-07-26 | — | — | CN | disclosed |
| US-5985225-A | COMPRISING COBALT-LOADED ZEOLITE NOT SHOWING A RAMAN SPECTRAL BAND ASSIGNABLE TO COBALT OXIDE | OSAKA GAS COMPANY LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| WO-1997012663-A1 | NITROGEN OXIDES REDUCTION CATALYST AND PROCESS FOR REDUCING NITROGEN OXIDES IN EXHAUST GAS | OSAKA GAS COMPANY LIMITED (JP) | 1997-04-10 | — | — | WO | disclosed |
| EP-0766992-A1 | Nitrogen oxides reduction catalyst and process for reducing nitrogen oxides in exhaust gas | ENIRICERCHE S.p.A. (IT) | 1997-04-09 | — | — | EP | disclosed |
| CN-1133593-A | Piperazine compounds for use in therapy | WELLCOME FOUND (GB) | 1996-10-16 | — | — | CN | disclosed |
| WO-1996029140-A1 | NITROGEN OXIDE-REDUCING CATALYST AND PROCESS FOR REDUCING NITROGEN OXIDES IN EXHAUST GAS | OSAKA GAS COMPANY LIMITED (JP) | 1996-09-26 | — | — | WO | disclosed |
| EP-0732140-A1 | Nitrogen oxide-reducing catalyst and process for reducing nitrogen oxides in exhaust gas | ENIRICERCHE S.p.A. (IT) | 1996-09-18 | — | — | EP | disclosed |
| WO-1994029300-A1 | PYRAZOLE FUNGICIDES 3-SUBSTITUTED BY A HETEROCYCLIC RING | RHONE POULENC AGROCHIMIE (FR) | 1994-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034146-A1 | ELECTRO-PHOTOCHEMICAL SYNTHESIS OF 1,2,4-TRIAZOLO-[4,3-A]PYRAZINE | CYP4Z1, TYR, PPOX | TSHR 1442/4885NFKB1 2192/4885KCNA1 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.