Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167867 | 0.91 | CPT1A (0.38) | L3MBTL1CPT1ACPT2 | |
| SCHEMBL6166634 | 0.85 | ALDH1A1 (0.40) | TRPV1ALDH1A1HPGDL3MBTL1CPT1A | |
| SCHEMBL17396055 | 0.83 | GCK (0.42) | TRPV1ALDH1A1HPGDL3MBTL1CPT1A | |
| SCHEMBL6166218 | 0.81 | KDM4E (0.36) | ALDH1A1HPGDL3MBTL1LMNAMAPT | |
| SCHEMBL6166202 | 0.76 | LMNA (0.40) | ALDH1A1HPGDL3MBTL1LMNAMAPT | |
| SCHEMBL6169344 | 0.76 | DAGLA (0.41) | ALDH1A1CPT1AMAPK1CPT2 | |
| SCHEMBL6167911 | 0.73 | L3MBTL1 (0.37) | ALDH1A1HPGDL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL6169351 | 0.73 | TRPV1 (0.43) | TRPV1ALDH1A1HPGDCPT1ALMNA | |
| SCHEMBL6166850 | 0.73 | HRH2 (0.35) | L3MBTL1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL6166739 | 0.73 | CHRM2 (0.37) | ALDH1A1L3MBTL1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349850-B1 | SODIUM CHANNEL MODULATORS DERIVED FROM 2-PIPERIDYLIMIDAZOLES | SOD CONSEILS RECH APPLIC (FR) | 2005-09-07 | — | — | EP | claimed |