Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164647 | 0.83 | CHRM2 (0.31) | — | |
| SCHEMBL6168214 | 0.83 | CTSA (0.34) | — | |
| SCHEMBL6168666 | 0.81 | — | — | |
| SCHEMBL6166906 | 0.79 | ADRA2A (0.33) | — | |
| SCHEMBL6168251 | 0.79 | CCR1 (0.30) | — | |
| SCHEMBL6168206 | 0.79 | ACKR3 (0.31) | — | |
| SCHEMBL6167494 | 0.78 | CCR1 (0.40) | — | |
| SCHEMBL6167961 | 0.77 | CCR1 (0.31) | — | |
| SCHEMBL6167169 | 0.77 | MAOA (0.38) | — | |
| SCHEMBL6168510 | 0.77 | CCR1 (0.34) | KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1498417-A1 | Heterocyclic amide derivatives | Pfizer Products Inc. (US) | 2005-01-19 | — | — | EP | disclosed |
| US-20040087571-A1 | Methods of using CCR1 antagonists as immunomodulatory agents | PFIZER INC | 2004-05-06 | — | — | US | disclosed |
| US-6689886-B2 | TREATMENT OF INFLAMMATION AND OTHER IMMUNE DISORDERS | PFIZER INC. | 2004-02-10 | — | — | US | disclosed |
| US-20030204086-A1 | Novel heterocyclic amide derivatives | BROWN MATTHEW F (US) | 2003-10-30 | — | — | US | disclosed |
| US-6548671-B2 | Treating autoimmune diseases, inflammatory conditions, allergies, infections, viral diseases, bronchitis, transplant tissue rejection, atherosclerosis, restenosis, HIV infectivity, and granulomatous | PFIZER INC | 2003-04-15 | — | — | US | disclosed |
| US-20020132810-A1 | Novel heterocyclic amide derivatives | BROWN MATTHEW F (US) | 2002-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030204086-A1 | Novel heterocyclic amide derivatives | HAX1, ARG1, CXCR2 | MEN1 4376/4885KMT2A 656/4885NPSR1 1622/4885 |
| US-20040087571-A1 | Methods of using CCR1 antagonists as immunomodulatory agents | CCR1, CCR3, CCRL2 | MEN1 3087/4885KMT2A 2266/4885NPSR1 1141/4885 |
| US-20020132810-A1 | Novel heterocyclic amide derivatives | ARG1, IL4, ARG2 | MEN1 3718/4885KMT2A 1196/4885NPSR1 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.