Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168750 | 0.80 | LMNA (0.46) | ACACBMEN1HPGDKMT2AENPP2 | |
| SCHEMBL6169640 | 0.79 | AR (0.42) | ACHEMEN1KMT2A | |
| SCHEMBL2722964 | 0.77 | MEN1 (0.49) | ACACBMEN1KMT2A | |
| SCHEMBL6167006 | 0.77 | ALDH1A1 (0.42) | SRD5A1PTGER4PTGER2MEN1HPGD | |
| SCHEMBL6167129 | 0.74 | XDH (0.43) | — | |
| SCHEMBL6168895 | 0.73 | CYP3A4 (0.47) | ACACBMEN1KMT2A | |
| SCHEMBL25142596 | 0.72 | CHKA (0.61) | SIRT2SIRT1KDM1A | |
| SCHEMBL6169204 | 0.72 | ACACB (0.43) | ACACBPOLB | |
| SCHEMBL6169451 | 0.72 | PTGER4 (0.42) | PTGER4PTGER2MEN1KMT2APOLB | |
| SCHEMBL18173436 | 0.71 | KDM1A (0.46) | SIRT2SIRT1KDM1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530472-A1 | ISOQUINOLINE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004014379-A1 | ISOQUINOLINE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |