Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28365758 | 1.00 | LTA4H (0.51) | LTA4HMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL10262594 | 0.94 | LTA4H (0.47) | LTA4HSMN1; SMN2ALDH1A1RAB9ANR5A1 | |
| SCHEMBL25877173 | 0.89 | NR5A1 (0.56) | LTA4HNPC1RAB9ANR5A1TP53 | |
| SCHEMBL1818269 | 0.88 | AHR (0.43) | LTA4HSMN1; SMN2ALDH1A1NR5A1TSHR | |
| SCHEMBL28370253 | 0.88 | AHR (0.43) | LTA4HSMN1; SMN2ALDH1A1NR5A1TSHR | |
| SCHEMBL15763651 | 0.88 | LTA4H (0.42) | LTA4HMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1812486 | 0.88 | KIF11 (0.49) | LTA4HMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL10261885 | 0.87 | LTA4H (0.47) | LTA4HMEN1KMT2AALDH1A1HTT | |
| SCHEMBL1959801 | 0.87 | FAAH (0.47) | LTA4HSMN1; SMN2KDM4EALDH1A1NR5A1 | |
| SCHEMBL719359 | 0.86 | ALDH1A1 (0.55) | LTA4HMEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3621958-B9 | PHOTOCHROMIC INDENO FUSED PHENANTHRENOPYRAN COMPOUNDS | TRANSITIONS OPTICAL LTD (IE) | 2024-09-25 | — | — | EP | disclosed |
| EP-3621958-B1 | PHOTOCHROMIC INDENO FUSED PHENANTHRENOPYRAN COMPOUNDS | TRANSITIONS OPTICAL LTD (IE) | 2024-07-10 | — | — | EP | disclosed |
| CN-113150007-B | Photochromic indeno-fused ring pyran compounds | 光学转变公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-110730778-B | Photochromic indeno-fused phenanthropyran compounds | 光学转变有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-11453654-B2 | Photochromic indeno fused phenanthrenopyran compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2022-09-27 | — | — | US | disclosed |
| EP-3268375-B1 | PHOTOCHROMIC THIENOCHROMENE COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2022-06-15 | — | — | EP | disclosed |
| EP-3071576-B9 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2021-12-22 | — | — | EP | disclosed |
| US-20210317129-A1 | Indolenaphthopyrans | TRANSITIONS OPTICAL, LTD. (IE) | 2021-10-14 | — | — | US | disclosed |
| EP-3071576-B1 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2021-08-18 | — | — | EP | disclosed |
| CN-113227099-A | Articles comprising indole naphthopyrans | 光学转变有限公司 | 2021-08-06 | — | — | CN | disclosed |
| US-20150141661-A1 | Photochromic Indeno-Fused Ring Pyran Compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-05-21 | — | — | US | disclosed |
| US-20150141663-A1 | Fused Ring Indeno Compounds For Preparation Of Photochromic Compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-05-21 | — | — | US | disclosed |
| US-20150141662-A1 | Method Of Preparing Fused Ring Indeno Compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-05-21 | — | — | US | disclosed |
| EP-2651914-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2015-05-13 | — | — | EP | disclosed |
| US-9029565-B1 | Fused ring indeno compounds for preparation of photochromic compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-8920928-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| EP-2651914-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | Transitions Optical, Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082999-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20120156508-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120153333-A1 | Light-Emitting Device and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141662-A1 | Method Of Preparing Fused Ring Indeno Compounds | INHA, INTS9, CA9 | LTA4H 283/4885MEN1 657/4885KMT2A 1445/4885 |
| US-20150141663-A1 | Fused Ring Indeno Compounds For Preparation Of Photochromic Compounds | IPO5, INCENP, NQO1 | LTA4H 1836/4885MEN1 2514/4885KMT2A 1702/4885 |
| US-20210317129-A1 | Indolenaphthopyrans | AHR, TDO2, TPH2 | LTA4H 2688/4885MEN1 3107/4885KMT2A 2760/4885 |
| US-20150141661-A1 | Photochromic Indeno-Fused Ring Pyran Compounds | INF2, INCENP, RB1 | LTA4H 2078/4885MEN1 1330/4885KMT2A 1384/4885 |
| US-11453654-B2 | Photochromic indeno fused phenanthrenopyran compounds | ALDH1A2, RB1, INCENP | LTA4H 1820/4885MEN1 1633/4885KMT2A 1736/4885 |
| US-20120156508-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | CRY2, CRY1, IPO4 | LTA4H 691/4885MEN1 3275/4885KMT2A 2088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.