Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170797 | 0.80 | APP (0.47) | L3MBTL1LMNAMAPTKDM4EMIF | |
| SCHEMBL719359 | 0.72 | ALDH1A1 (0.55) | ACSS2LMNAKDM4EMEN1ALDH1A1 | |
| SCHEMBL28673732 | 0.72 | APP (0.46) | L3MBTL1LMNAMAPTAPPMAPK1 | |
| SCHEMBL11572643 | 0.71 | CYP1A1 (0.42) | ACSS2MAPTMEN1ALDH1A1CYP3A4 | |
| SCHEMBL1812486 | 0.71 | KIF11 (0.49) | ACSS2LMNAMAPTKDM4EMEN1 | |
| SCHEMBL7815233 | 0.71 | LMNA (0.56) | L3MBTL1LMNAMAPTKDM4EMAPK1 | |
| SCHEMBL6170793 | 0.69 | MEN1 (0.35) | LMNAKDM4EAPPMEN1ALDH1A1 | |
| SCHEMBL9933229 | 0.69 | LTA4H (0.51) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL28365758 | 0.69 | LTA4H (0.51) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5391794 | 0.67 | ALDH1A1 (0.61) | L3MBTL1LMNAKDM4EAPPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112263-A1 | POLYMERIZABLE POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015629-A1 | POLYMERIZABLE POLYALKOXYLATED NAPHTHOPYRANS | PPG INDUSTRIES OHIO, INC. (US) | 2000-03-23 | — | — | WO | disclosed |