Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12599169 | 0.75 | MGLL (0.54) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| N-Ethylmaleimide SCHEMBL9487550 | 0.74 | MGLL (0.84) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL28493448 | 0.73 | MGLL (0.52) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL19901567 | 0.72 | MGLL (0.36) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL19242844 | 0.72 | MGLL (0.50) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL6754720 | 0.72 | NPSR1 (0.45) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL14944992 | 0.72 | MGLL (0.62) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL5826263 | 0.71 | — | — | |
| Dimethylamine SCHEMBL181615 | 0.70 | MGLL (0.59) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL23181692 | 0.69 | MGLL (0.68) | MGLLALDH1A1LMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9561290-B2 | Functionalized thieno-indole derivatives for the treatment of cancer | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2017-02-07 | — | — | US | disclosed |
| US-9492553-B2 | Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods | GENENTECH, INC. (US) | 2016-11-15 | — | — | US | disclosed |
| US-9242010-B2 | Living copolymer-protein/peptide hybrids for biomedical applications | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2016-01-26 | — | — | US | disclosed |
| US-20150080316-A1 | FUNCTIONALIZED THIENO-INDOLE DERIVATIVES FOR THE TREATMENT OF CANCER | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-03-19 | — | — | US | disclosed |
| US-8962342-B2 | Near-infrared dyes as surface enhanced raman scattering reporters | BECKTON, DICKINSON AND COMPANY (US) | 2015-02-24 | — | — | US | disclosed |
| US-20140227299-A1 | NEMORUBICIN METABOLITE AND ANALOG REAGENTS, ANTIBODY-DRUG CONJUGATES AND METHODS | GENENTECH, INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-8742076-B2 | Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods | GENENTECH, INC. (US) | 2014-06-03 | — | — | US | disclosed |
| US-20130143815-A1 | GROWTH HORMONE CONJUGATES | NOVO NORDISK HEALTH CARE AG (CH) | 2013-06-06 | — | — | US | disclosed |
| US-8129525-B2 | Long wavelength thiol-reactive fluorophores | BECTON DICKINSON AND COMPANY (US) | 2012-03-06 | — | — | US | disclosed |
| US-8071794-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON AND COMPANY (US) | 2011-12-06 | — | — | US | disclosed |
| US-20110262991-A1 | Living Copolymer-Protein/Peptide Hybrids for Biomedical Applications | THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK | 2011-10-27 | — | — | US | disclosed |
| US-20110184168-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2011-07-28 | — | — | US | disclosed |
| US-20110076287-A1 | NEMORUBICIN METABOLITE AND ANALOG REAGENTS, ANTIBODY-DRUG CONJUGATES AND METHODS | GENENTECH, INC. | 2011-03-31 | — | — | US | disclosed |
| US-20110076287-A1 | NEMORUBICIN METABOLITE AND ANALOG REAGENTS, ANTIBODY-DRUG CONJUGATES AND METHODS | GENENTECH, INC. | 2011-03-31 | — | — | US | disclosed |
| US-7767821-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2010-08-03 | — | — | US | disclosed |
| US-20100167417-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100003763-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2010-01-07 | — | — | US | disclosed |
| US-7563891-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2009-07-21 | — | — | US | disclosed |
| EP-2036953-A2 | Long wavelength thiol-reactive fluorophores | Becton, Dickinson & Company (US) | 2009-03-18 | — | — | EP | disclosed |
| US-20080305489-A1 | NEAR-INFRARED DYES AS SURFACE ENHANCED RAMAN SCATTERING REPORTERS | BECTON, DICKINSON AND COMPANY (US) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167417-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | NUCB2, NDC1, NCBP1 | MGLL 4854/4885ALDH1A1 1435/4885LMNA 1772/4885 |
| US-20140227299-A1 | NEMORUBICIN METABOLITE AND ANALOG REAGENTS, ANTIBODY-DRUG CONJUGATES AND METHODS | BCR, CD79B, MYADM | MGLL 2895/4885ALDH1A1 435/4885LMNA 237/4885 |
| US-20150080316-A1 | FUNCTIONALIZED THIENO-INDOLE DERIVATIVES FOR THE TREATMENT OF CANCER | NTSR1, HRH4, HTR4 | MGLL 4239/4885ALDH1A1 1402/4885LMNA 2663/4885 |
| US-20100003763-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | NUCB2, NDC1, NCBP1 | MGLL 4854/4885ALDH1A1 1435/4885LMNA 1772/4885 |
| US-20110076287-A1 | NEMORUBICIN METABOLITE AND ANALOG REAGENTS, ANTIBODY-DRUG CONJUGATES AND METHODS | BCR, CD79B, MYADM | MGLL 2895/4885ALDH1A1 435/4885LMNA 237/4885 |
| US-20110184168-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | NUCB2, NDC1, NCBP1 | MGLL 4854/4885ALDH1A1 1435/4885LMNA 1772/4885 |
| US-20130143815-A1 | GROWTH HORMONE CONJUGATES | GHRHR, GHSR, GHITM | MGLL 1579/4885ALDH1A1 3638/4885LMNA 4760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.