Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201493 | 0.84 | LMNA (0.46) | KMT2ACYP2C9CYP2C19EPHX2MGAM | |
| SCHEMBL6201652 | 0.77 | ALDH1A1 (0.43) | POLBKMT2ATP53NPC1RAB9A | |
| SCHEMBL6201073 | 0.75 | CYP19A1 (0.53) | POLBKMT2ACYP2C9CYP2C19MGAM | |
| SCHEMBL6202063 | 0.74 | MDM2 (0.46) | KMT2ACYP2C9CYP2C19KDM4EVNN1 | |
| SCHEMBL2142802 | 0.71 | PDPK1 (0.55) | POLBKMT2ACYP2C9CYP2C19TP53 | |
| SCHEMBL6204077 | 0.70 | MGAM (0.50) | POLBKMT2ACYP2C9CYP2C19MGAM | |
| SCHEMBL10908660 | 0.67 | CYP1A2 (0.50) | KMT2ACYP2C9CYP2C19KDM4ENPC1 | |
| SCHEMBL10906842 | 0.67 | RAB9A (0.65) | KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL10908679 | 0.67 | RAB9A (0.65) | KMT2ACYP2C9CYP2C19KDM4ENPC1 | |
| SCHEMBL7363506 | 0.65 | TBXAS1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |