Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.31 |
| ▸ | PRUNE1 | Q86TP1 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204719 | 0.87 | PGK1 (0.33) | — | |
| SCHEMBL6205408 | 0.86 | PRUNE1 (0.35) | HMGCREHMT2EHMT1PRUNE1 | |
| SCHEMBL6204811 | 0.85 | PRUNE1 (0.32) | PRUNE1 | |
| SCHEMBL6203495 | 0.83 | PRUNE1 (0.35) | PRUNE1 | |
| SCHEMBL6203460 | 0.83 | MTOR (0.32) | PRUNE1 | |
| SCHEMBL6203171 | 0.77 | CCNE1 (0.37) | EGFR | |
| SCHEMBL6202760 | 0.77 | CDK1 (0.40) | PRUNE1EGFR | |
| SCHEMBL3445672 | 0.76 | CDK2 (0.46) | — | |
| SCHEMBL6203475 | 0.75 | SMN1; SMN2 (0.45) | EGFR | |
| SCHEMBL3444371 | 0.75 | CDK2 (0.36) | EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |