Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907338 | 0.89 | NAAA (0.37) | ALDH1A1SPHK1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL6204538 | 0.84 | NOS3 (0.39) | ALDH1A1ACEHTTSMN1; SMN2 | |
| SCHEMBL28055445 | 0.82 | ACE (0.39) | MEN1KMT2AALDH1A1ELANEBCHE | |
| SCHEMBL6338204 | 0.76 | ELANE (0.38) | MEN1KMT2AALDH1A1CYP2C9ELANE | |
| SCHEMBL27658289 | 0.76 | ACE (0.38) | ALDH1A1ELANECHRNB2CHRNA7CHRNA4 | |
| SCHEMBL11035603 | 0.75 | FAAH (0.44) | MEN1KMT2ACYP2C9ELANEBCHE | |
| SCHEMBL1907356 | 0.74 | CHRNB2 (0.42) | ALDH1A1CHRNB2CHRNA7CHRNA4CYP1A2 | |
| SCHEMBL6739162 | 0.73 | CHRNB2 (0.44) | ALDH1A1CHRNB2CHRNA7CHRNA4CYP1A2 | |
| SCHEMBL868861 | 0.72 | ALDH1A1 (0.36) | ALDH1A1CHRNB2CHRNA7CHRNA4CYP1A2 | |
| SCHEMBL28354841 | 0.72 | GBA1 (0.42) | ALDH1A1BCHECHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534681-A1 | SUBSTITUTED QUINOLINE CCR5 RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-06-01 | — | — | EP | claimed |
| WO-2004002960-A1 | SUBSTITUTED QUINOLINE CCR5 RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-01-08 | — | — | WO | claimed |
| EP-1534681-A1 | SUBSTITUTED QUINOLINE CCR5 RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004002960-A1 | SUBSTITUTED QUINOLINE CCR5 RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-01-08 | — | — | WO | disclosed |