Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207660 | 0.88 | GRM5 (0.43) | GRM5FFAR1EGLN1 | |
| SCHEMBL6208783 | 0.86 | ADORA3 (0.42) | GRM5FFAR1 | |
| SCHEMBL6212636 | 0.84 | GRM5 (0.47) | GRM5 | |
| SCHEMBL6198861 | 0.83 | GRM5 (0.44) | GRM5FFAR1 | |
| SCHEMBL6208345 | 0.80 | ADORA3 (0.41) | GRM5 | |
| SCHEMBL6209784 | 0.79 | GABRA2 (0.37) | GRM5L3MBTL1 | |
| SCHEMBL6208213 | 0.79 | GRM5 (0.43) | GRM5FFAR1 | |
| SCHEMBL6207945 | 0.78 | TDP1 (0.34) | TDP1 | |
| SCHEMBL6208296 | 0.75 | GRM5 (0.45) | GRM5 | |
| SCHEMBL6200156 | 0.70 | GRM5 (0.43) | GRM5FFAR1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349839-B1 | PHENYLETHENYL OR PHENYLETHINYL DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2005-02-09 | — | — | EP | claimed |