Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208783 | 0.84 | ADORA3 (0.42) | GRM5LMNAALDH1A1KDM4ENPC1 | |
| SCHEMBL6208213 | 0.82 | GRM5 (0.43) | GRM5KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL6199507 | 0.82 | GRM5 (0.53) | GRM5KMT2APOLBLMNAPKM | |
| SCHEMBL6208345 | 0.80 | ADORA3 (0.41) | GRM5LMNAALDH1A1KDM4ENPC1 | |
| SCHEMBL6207945 | 0.79 | TDP1 (0.34) | KMT2APOLBLMNAALDH1A1KDM4E | |
| SCHEMBL6207660 | 0.78 | GRM5 (0.43) | GRM5KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6209784 | 0.77 | GABRA2 (0.37) | GRM5KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL6209016 | 0.75 | GRM5 (0.43) | GRM5 | |
| SCHEMBL4083809 | 0.74 | CACNA1F (0.42) | KMT2APOLBLMNAALDH1A1KDM4E | |
| SCHEMBL6212636 | 0.74 | GRM5 (0.47) | GRM5KMT2APOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349839-B1 | PHENYLETHENYL OR PHENYLETHINYL DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2005-02-09 | — | — | EP | claimed |