Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208213 | 0.88 | GRM5 (0.43) | GABRA2GABRB2KMT2AOPRM1LMNA | |
| SCHEMBL6208783 | 0.88 | ADORA3 (0.42) | GABRA2GABRB2HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL6208345 | 0.86 | ADORA3 (0.41) | GABRA2GABRB2HPGDSMN1; SMN2ACACB | |
| SCHEMBL6207945 | 0.83 | TDP1 (0.34) | KMT2AMEN1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL6207660 | 0.82 | GRM5 (0.43) | KMT2ASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6202119 | 0.81 | GABRA2 (0.44) | GABRA2GABRB2KMT2AMEN1HTT | |
| SCHEMBL6209016 | 0.79 | GRM5 (0.43) | L3MBTL1GRM5 | |
| SCHEMBL6212636 | 0.78 | GRM5 (0.47) | KMT2AMEN1SMN1; SMN2ACACBPOLB | |
| SCHEMBL6207861 | 0.78 | ALDH1A1 (0.35) | KMT2AMEN1HTTHPGDSMN1; SMN2 | |
| SCHEMBL6208296 | 0.77 | GRM5 (0.45) | KMT2AMEN1SMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349839-B1 | PHENYLETHENYL OR PHENYLETHINYL DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2005-02-09 | — | — | EP | claimed |