SCHEMBL6209049

SCHEMBL6209049

CCCC(C)CC(C)N=C1C=CC(=Nc2ccccc2)C=C1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13067055 0.88 LMNA (0.40) LMNA
SCHEMBL1241941 0.83 ALDH1A1 (0.31) LMNA
SCHEMBL14150195 0.82 LMNA (0.36) LMNA
SCHEMBL6208646 0.81 LMNA (0.33) LMNATRPA1
SCHEMBL6208289 0.81 ALDH1A1 (0.36) LMNA
SCHEMBL6817759 0.78 LMNA (0.32) LMNA
SCHEMBL7093744 0.73 ALDH1A1 (0.33) LMNA
SCHEMBL755432 0.69 ALDH1A1 (0.47) LMNA
SCHEMBL6210004 0.67 LMNA (0.33) LMNA
SCHEMBL6209034 0.67 LMNA (0.34) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9090526-B2 Synergistic combination for inhibiting polymerization of vinyl monomers NALCO COMPANY (US) 2015-07-28 US claimed
EP-1305279-B1 POLYMERIZATION INHIBITOR FOR VINYL-CONTAINING MATERIALS GE BETZ INC (US) 2005-02-23 EP claimed
JP-2004504369-A 2004-02-12 JP claimed
US-6592722-B2 Comprising a quinone diimide compound and a nitroxyl compound GE BETZ, INC. 2003-07-15 US claimed
EP-1305279-A2 POLYMERIZATION INHIBITOR FOR VINYL-CONTAINING MATERIALS GE Betz, Inc. (US) 2003-05-02 EP claimed
US-20030030035-A1 Polymerization inhibitor for vinyl-containing materials GE BETZ, INC. 2003-02-13 US claimed
WO-2002008161-A2 POLYMERIZATION INHIBITOR FOR VINYL-CONTAINING MATERIALS HERCULES INCORPORATED (US) 2002-01-31 WO claimed
US-9090526-B2 Synergistic combination for inhibiting polymerization of vinyl monomers NALCO COMPANY (US) 2015-07-28 US disclosed
EP-2726451-A2 SYNERGISTIC COMBINATION FOR INHIIBITING POLYMERIZATION OF VINYL MONOMERS Nalco Company (US) 2014-05-07 EP disclosed
WO-2012173925-A2 SYNERGISTIC COMBINATION FOR INHIIBITING POLYMERIZATION OF VINYL MONOMERS NALCO COMPANY (US) 2012-12-20 WO disclosed
US-20120316369-A1 SYNERGISTIC COMBINATION FOR INHIIBITING POLYMERIZATION OF VINYL MONOMERS ECOLAB USA INC. 2012-12-13 US disclosed
EP-1305279-B1 POLYMERIZATION INHIBITOR FOR VINYL-CONTAINING MATERIALS GE BETZ INC (US) 2005-02-23 EP disclosed
US-6592722-B2 Comprising a quinone diimide compound and a nitroxyl compound GE BETZ, INC. 2003-07-15 US disclosed
EP-1305279-A2 POLYMERIZATION INHIBITOR FOR VINYL-CONTAINING MATERIALS GE Betz, Inc. (US) 2003-05-02 EP disclosed
US-20030030035-A1 Polymerization inhibitor for vinyl-containing materials GE BETZ, INC. 2003-02-13 US disclosed
US-6447649-B1 SYNERGISTIC MIXTURE OF A QUINONE DIIMIDE AND HYDROQUINONE GE BETZ, INC. 2002-09-10 US disclosed
WO-2002008161-A2 POLYMERIZATION INHIBITOR FOR VINYL-CONTAINING MATERIALS HERCULES INCORPORATED (US) 2002-01-31 WO disclosed
US-5562863-A UTILIZING 2,6-DI-TERT-BUTYL-4-METHYLPHENOL AND SUBSTITUTED BENZOQUINONEDIIMIDE TO PREVENT STYRENE POLYMERIZATION BETZ LABORATORIES, INC. (US) 1996-10-08 US disclosed
US-5470440-A 2,6-di-tert-butyl-4-methylphenol and a substituted benzoquinonediimide BETZ LABORATORIES, INC. (US) 1995-11-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120316369-A1 SYNERGISTIC COMBINATION FOR INHIIBITING POLYMERIZATION OF VINYL MONOMERS QDPR, SDHA, BLVRB LMNA 2599/4885TRPA1 4407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.