Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 13/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619075 | 0.95 | SSTR4 (0.40) | DHFRDCPSSSTR4HTR1ADRD2 | |
| SCHEMBL15605504 | 0.94 | SSTR4 (0.42) | SSTR4MEN1KMT2A | |
| SCHEMBL627378 | 0.92 | SSTR4 (0.41) | SSTR4MEN1KMT2A | |
| SCHEMBL618830 | 0.92 | SSTR4 (0.41) | SSTR4MEN1KMT2A | |
| SCHEMBL621093 | 0.91 | SSTR4 (0.40) | SSTR4MEN1KMT2A | |
| SCHEMBL618704 | 0.91 | GABRP (0.39) | DHFRDCPSSSTR4HTR1ADRD2 | |
| SCHEMBL10259335 | 0.90 | SSTR4 (0.40) | SSTR4MEN1KMT2A | |
| SCHEMBL10257618 | 0.90 | SSTR4 (0.40) | SSTR4MEN1KMT2A | |
| SCHEMBL10285705 | 0.90 | SSTR4 (0.40) | SSTR4MEN1KMT2A | |
| SCHEMBL27103197 | 0.90 | SSTR4 (0.40) | SSTR4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603098-B1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED (US) | 2025-08-06 | — | — | EP | disclosed |
| US-20240065302-A1 | SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF | FIRMENICH INCORPORATED | 2024-02-29 | — | — | US | disclosed |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | FIREMENICH INCORPORATED (US) | 2021-09-28 | — | — | US | disclosed |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | FIREMENICH INCORPORATED (US) | 2021-09-28 | — | — | US | disclosed |
| CN-106107406-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 弗门尼舍公司 | 2020-06-09 | — | — | CN | disclosed |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2019-07-11 | — | — | US | disclosed |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2019-07-11 | — | — | US | disclosed |
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-20180086751-A1 | SWEETENER COMPOSITION | SENOMYX, INC. | 2018-03-29 | — | — | US | disclosed |
| US-8815956-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8815956-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| EP-2742026-A1 | SWEET FLAVOR MODIFIER | Senomyx, Inc. (US) | 2014-06-18 | — | — | EP | disclosed |
| WO-2013158928-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2013-10-24 | — | — | WO | disclosed |
| WO-2013025560-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2013-02-21 | — | — | WO | disclosed |
| WO-2013025560-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2013-02-21 | — | — | WO | disclosed |
| US-20130041046-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2013-02-14 | — | — | US | disclosed |
| US-20130041046-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2013-02-14 | — | — | US | disclosed |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | DHFR 2350/4885DCPS 919/4885SSTR4 2147/4885 |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | DHFR 2350/4885DCPS 919/4885SSTR4 2147/4885 |
| US-20130041046-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | DHFR 2252/4885DCPS 1074/4885SSTR4 764/4885 |
| US-20180086751-A1 | SWEETENER COMPOSITION | TAS2R50, TAS1R2, TAS2R10 | DHFR 2724/4885DCPS 956/4885SSTR4 612/4885 |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | DHFR 2350/4885DCPS 919/4885SSTR4 2147/4885 |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | DHFR 2350/4885DCPS 919/4885SSTR4 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.