Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211364 | 0.92 | DPP4 (0.45) | DPP4NAMPTPTAFRLMNAKMT2A | |
| SCHEMBL6258369 | 0.91 | LMNA (0.44) | DPP4NAMPTCXCR3LMNAALDH1A1 | |
| SCHEMBL6212946 | 0.90 | RAB9A (0.47) | DPP4NAMPTLMNAKMT2AMEN1 | |
| SCHEMBL6211394 | 0.90 | LMNA (0.40) | DPP4NAMPTPTAFRLMNAKMT2A | |
| SCHEMBL6212587 | 0.90 | NAMPT (0.42) | DPP4NAMPTLMNAALDH1A1DRD3 | |
| SCHEMBL5941964 | 0.88 | PKM (0.38) | DPP4NAMPTLMNAALDH1A1TSHR | |
| SCHEMBL6209651 | 0.88 | LMNA (0.42) | DPP4NAMPTCXCR3LMNACHRNB4 | |
| SCHEMBL6259546 | 0.87 | ALDH1A1 (0.46) | NAMPTLMNAALDH1A1MAPTTSHR | |
| SCHEMBL6209890 | 0.85 | DPP4 (0.37) | DPP4NAMPTPTAFRLMNAALDH1A1 | |
| SCHEMBL6212092 | 0.81 | PREP (0.48) | DPP4NAMPTLMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |