Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 4/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211238 | 0.88 | MAPK14 (0.35) | F10MAPK14ALDH1A1LMNAITGB3 | |
| SCHEMBL6211364 | 0.87 | DPP4 (0.45) | DPP4ALDH1A1PTAFRLMNANAMPT | |
| SCHEMBL6212946 | 0.86 | RAB9A (0.47) | DPP4ALDH1A1LMNANAMPTSMYD3 | |
| SCHEMBL6211394 | 0.85 | LMNA (0.40) | DPP4ALDH1A1PTAFRLMNANAMPT | |
| SCHEMBL5941964 | 0.85 | PKM (0.38) | DPP4ALDH1A1LMNANAMPTDRD3 | |
| SCHEMBL6209824 | 0.85 | DPP4 (0.47) | DPP4ALDH1A1PTAFRLMNANAMPT | |
| SCHEMBL6212587 | 0.85 | NAMPT (0.42) | DPP4ALDH1A1LMNANAMPTDRD2 | |
| SCHEMBL6259546 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNANAMPTDRD2DRD3 | |
| SCHEMBL6258369 | 0.83 | LMNA (0.44) | DPP4ALDH1A1LMNANAMPTDRD2 | |
| SCHEMBL6211397 | 0.78 | SMYD3 (0.35) | F10MAPK14ALDH1A1PTAFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |