Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.45 |
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212946 | 0.92 | RAB9A (0.47) | DPP4NAMPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6211394 | 0.92 | LMNA (0.40) | DPP4NAMPTLMNAHDAC3ALDH1A1 | |
| SCHEMBL6209824 | 0.92 | DPP4 (0.47) | DPP4NAMPTLMNAALDH1A1MEN1 | |
| SCHEMBL6212587 | 0.92 | NAMPT (0.42) | DPP4NAMPTLMNAHDAC3HDAC1 | |
| SCHEMBL5941964 | 0.90 | PKM (0.38) | DPP4NAMPTLMNAALDH1A1 | |
| SCHEMBL6259546 | 0.89 | ALDH1A1 (0.46) | NAMPTLMNAHDAC3HDAC1ALDH1A1 | |
| SCHEMBL6210118 | 0.89 | DPP4 (0.44) | DPP4NAMPTLMNAHDAC3HDAC1 | |
| SCHEMBL6258369 | 0.88 | LMNA (0.44) | DPP4NAMPTLMNAHDAC3HDAC1 | |
| SCHEMBL6213622 | 0.87 | LMNA (0.38) | DPP4NAMPTLMNAALDH1A1CYP3A4 | |
| SCHEMBL6209890 | 0.87 | DPP4 (0.37) | DPP4NAMPTLMNAALDH1A1SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |