Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA4 | P22748 | 5/20 | 0.33 |
| ▸ | CA6 | P23280 | 5/20 | 0.33 |
| ▸ | MAP3K9 | P80192 | 3/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 3/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | STK17B | O94768 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18049808 | 0.78 | MAP3K9 (0.36) | MAP3K9MAP3K11PNMTKDRNPC1 | |
| SCHEMBL7784188 | 0.75 | TRPM4 (0.44) | ALOX5CA1CA2CA4CA6 | |
| SCHEMBL30883365 | 0.72 | TERT (0.37) | CA1CA2CA4CA6MAP3K9 | |
| SCHEMBL6331258 | 0.72 | TERT (0.37) | CA1CA2CA4CA6MAP3K9 | |
| SCHEMBL6208162 | 0.71 | MAP3K9 (0.47) | ALOX5CA1CA2CA4CA6 | |
| SCHEMBL28524402 | 0.70 | PNMT (0.41) | ALOX5CA1CA2CA4CA6 | |
| SCHEMBL38656382 | 0.69 | KDM4E (0.46) | CA1CA2CA4CA6MAP3K9 | |
| SCHEMBL12774644 | 0.68 | ALDH1A1 (0.57) | ALOX5KDRALDH1A1STK17BMIF | |
| SCHEMBL7789620 | 0.68 | MEN1 (0.45) | ALOX5CA1CA2CA4CA6 | |
| SCHEMBL7789933 | 0.67 | ALDH1A1 (0.46) | ALOX5CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881850-B2 | Heterocyclically annellated indenochromene derivatives | RODENSTOCK GMBH (DE) | 2005-04-19 | — | — | US | disclosed |
| EP-1144416-B1 | HETEROCYCLICALLY ANELLATED INDENOCHROMENE DERIVATIVES | RODENSTOCK GMBH (DE) | 2005-03-02 | — | — | EP | disclosed |
| US-20040092743-A1 | Heterocyclically annellated indenochromene derivatives | OPTISCHE WERKE G. RODENSTOCK | 2004-05-13 | — | — | US | disclosed |
| US-6660727-B1 | Photochromic heterocyclically anellated indenochromene compounds | RODENSTOCK GMBH (DE) | 2003-12-09 | — | — | US | disclosed |
| EP-1144416-A1 | HETEROCYCLICALLY ANELLATED INDENOCHROMENE DERIVATIVES | Optische Werke G. Rodenstock (DE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2001034609-A1 | HETEROCYCLICALLY ANELLATED INDENOCHROMENE DERIVATIVES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092743-A1 | Heterocyclically annellated indenochromene derivatives | ALDH1A2, INF2, CYP1B1 | ALOX5 1037/4885CA1 3003/4885CA2 1408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.