Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439233 | 0.93 | ALDH1A1 (0.48) | ALDH1A1GAAPOLBNPSR1CYP1A2 | |
| SCHEMBL29674641 | 0.93 | ALDH1A1 (0.48) | ALDH1A1GAAPOLBNPSR1CYP1A2 | |
| SCHEMBL11148117 | 0.91 | ALDH1A1 (0.52) | ALDH1A1GAAPOLBNPSR1CYP1A2 | |
| SCHEMBL11149357 | 0.88 | ALDH1A1 (0.44) | ALDH1A1GAAPOLBNPSR1CYP1A2 | |
| SCHEMBL24440500 | 0.86 | ALDH1A1 (0.50) | ALDH1A1GAAPOLBNPSR1CA12 | |
| SCHEMBL11151949 | 0.84 | ALDH1A1 (0.53) | ALDH1A1GAAPOLBNPSR1CYP1A2 | |
| SCHEMBL24440151 | 0.84 | ALDH1A1 (0.48) | ALDH1A1GAAPOLBNPSR1CA12 | |
| SCHEMBL24439280 | 0.83 | ALDH1A1 (0.41) | ALDH1A1GAAPOLBNPSR1CYP1A2 | |
| SCHEMBL11325748 | 0.80 | ALDH1A1 (0.57) | ALDH1A1GAAPOLBNPSR1CYP1A2 | |
| SCHEMBL11267535 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GAAPOLBNPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4393046-A | PYROMELLITIMIDE | MERCK & CO., INC. (US) | 1983-07-12 | — | — | US | claimed |
| US-4212880-A | INCREASE FEED EFFICIENCY | MERCK & CO., INC. (US) | 1980-07-15 | — | — | US | claimed |
| EP-3455299-B1 | COMPOSITIONS COMPRISING A POLYMERIC DYE AND A CYCLODEXTRIN AND USES THEREOF | SONY GROUP CORP (JP) | 2024-01-17 | — | — | EP | disclosed |
| EP-4217412-A1 | WASTE MITIGATION METHODS AND MATERIALS | Finite Research Ltd (GB) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022103281-A1 | METHANOGEN INHIBITORS | PASTORAL GREENHOUSE GAS RESEARCH LTD (NZ) | 2022-05-19 | — | — | WO | disclosed |
| WO-2022103281-A1 | METHANOGEN INHIBITORS | PASTORAL GREENHOUSE GAS RESEARCH LTD (NZ) | 2022-05-19 | — | — | WO | disclosed |
| WO-2022023916-A1 | WASTE MITIGATION METHODS AND MATERIALS | LI, Zhenzhen (CN) | 2022-02-03 | — | — | WO | disclosed |
| US-20210252156-A1 | METHODS OF TREATING NAUSEA UTILIZING SEMI-SOLID DELIVERY VEHICLE COMPOSITIONS COMPRISING GRANISETRON | HERON THERAPEUTICS INC (US) | 2021-08-19 | — | — | US | disclosed |
| EP-3834817-A1 | SEMI-SOLID DELIVERY VEHICLE AND PHARMACEUTICAL COMPOSITIONS | Heron Therapeutics, Inc. (US) | 2021-06-16 | — | — | EP | disclosed |
| US-20200405866-A1 | METHODS OF TREATING NAUSEA UTILIZING SEMI-SOLID DELIVERY VEHICLE COMPOSITIONS COMPRISING GRANISETRON | HERON THERAPEUTICS, INC. | 2020-12-31 | — | — | US | disclosed |
| US-20200392345-A1 | ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH RIGID SPACING GROUPS | SONY CORPORATION (JP) | 2020-12-17 | — | — | US | disclosed |
| EP-1280558-A2 | SEMI-SOLID DELIVERY VEHICLE AND PHARMACEUTICAL COMPOSITIONS | Advanced Polymer Systems, Inc. (US) | 2003-02-05 | — | — | EP | disclosed |
| US-20020176844-A1 | Bioerodible polyorthoesters containing hydrogen bonding groups | AP PHARMA, INC. | 2002-11-28 | — | — | US | disclosed |
| US-20020168336-A1 | Bioerodible polyorthoesters from dioxolane-based diketene acetals | HERON THERAPEUTICS, INC. (F/K/A A.P. PHARMA, INC.) | 2002-11-14 | — | — | US | disclosed |
| US-20020037300-A1 | Semi-solid delivery vehicle and pharmaceutical compositions | HERON THERAPEUTICS, INC. (F/K/A A.P. PHARMA, INC.) | 2002-03-28 | — | — | US | disclosed |
| WO-2001085139-A2 | SEMI-SOLID DELIVERY VEHICLE AND PHARMACEUTICAL COMPOSITIONS | ADVANCED POLYMER SYSTEMS, INC. (US) | 2001-11-15 | — | — | WO | disclosed |
| US-4549010-A | Bioerodible poly(ortho ester) thermoplastic elastomer from diketene diacetal | MERCK & CO., INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4393046-A | PYROMELLITIMIDE | MERCK & CO., INC. (US) | 1983-07-12 | — | — | US | disclosed |
| EP-0010441-B1 | THE USE OF SYMMETRICALLY SUBSTITUTED PYROMELLITIC DIIMIDES AS RUMINANT FEED ADDITIVES. COMPOSITIONS CONTAINING THESE FEED ADDITIVES | MERCK & CO. INC. (US) | 1982-04-21 | — | — | EP | disclosed |
| US-4212880-A | INCREASE FEED EFFICIENCY | MERCK & CO., INC. (US) | 1980-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037300-A1 | Semi-solid delivery vehicle and pharmaceutical compositions | LIPA, CEL, SORD | ALDH1A1 4412/4885GAA 943/4885POLB 1943/4885 |
| US-20200405866-A1 | METHODS OF TREATING NAUSEA UTILIZING SEMI-SOLID DELIVERY VEHICLE COMPOSITIONS COMPRISING GRANISETRON | LPXN, CRH, NTSR1 | ALDH1A1 4638/4885GAA 1004/4885POLB 2680/4885 |
| US-20020176844-A1 | Bioerodible polyorthoesters containing hydrogen bonding groups | PLOD3, HAO2, CD44 | ALDH1A1 174/4885GAA 964/4885POLB 2943/4885 |
| US-20210252156-A1 | METHODS OF TREATING NAUSEA UTILIZING SEMI-SOLID DELIVERY VEHICLE COMPOSITIONS COMPRISING GRANISETRON | LPXN, CRH, NTSR1 | ALDH1A1 4638/4885GAA 1004/4885POLB 2680/4885 |
| US-20020168336-A1 | Bioerodible polyorthoesters from dioxolane-based diketene acetals | HAAO, HAO2, HAO1 | ALDH1A1 121/4885GAA 991/4885POLB 3681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.