Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL946250 | 1.00 | TRPA1 (0.46) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL1845749 | 0.97 | TRPA1 (0.44) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL186618 | 0.97 | — | — | |
| Fluoride SCHEMBL4456415 | 0.77 | TSHR (0.53) | CYP2A6CYP1A2TSHRACHEALDH1A1 | |
| Fluoride SCHEMBL1335989 | 0.77 | TSHR (0.53) | CYP2A6CYP1A2TSHRACHEALDH1A1 | |
| SCHEMBL5494561 | 0.75 | TRPA1 (0.61) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| SCHEMBL40704 | 0.75 | — | — | |
| Fluoride SCHEMBL943942 | 0.74 | CYP1A2 (0.33) | TRPA1ATMCYP2A6CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL1847829 | 0.74 | TSHR (0.50) | CYP2A6CYP1A2TSHRACHEALDH1A1 | |
| Fluoride SCHEMBL943405 | 0.74 | ALDH1A1 (0.50) | CYP2A6CYP1A2TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958415-B2 | Synthesis of pentafluorosulfuranyl arylenes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2005-10-25 | — | — | US | disclosed |
| EP-1533297-A1 | Synthesis of pentafluorosulfuranyl arylenes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20050107632-A1 | Synthesis of pentafluorosulfuranyl arylenes | AIR PRODUCTS AND CHEMICALS, INC. | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107632-A1 | Synthesis of pentafluorosulfuranyl arylenes | TST, DHRS9, HDHD5 | TRPA1 581/4885ATM 3496/4885CYP2A6 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.